Date published: 2025-9-8

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PC-TP 抗体 (LB-6): sc-101309

4.5(2)
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说明书
  • PC-TP 抗体 LB-6 是小鼠单克隆 IgG2b (kappa轻链),PC-TP抗体,规格为100 µg/ml
  • 免疫human物种的重组PC-TP
  • 推荐用于 human 来源的PC-TP WB, IP 和 ELISA检测
  • 关于如何获取PC-TP (LB-6): sc-101309免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成PC-TP 抗体 (LB-6)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    関連項目

    PC-TP抗体(LB-6)是一种IgG2b κ小鼠单克隆PC-TP抗体(也称为PC-TP抗体),可通过WB、IP和ELISA检测来自人的PC-TP蛋白。PC-TP抗体(LB-6)为非共轭形式的抗PC-TP抗体。真核细胞含有磷脂转运蛋白,这些蛋白充当磷脂在膜之间的载体。在哺乳动物组织中,已发现三种具有不同特异性的转运蛋白:磷脂酰胆碱转运蛋白(PC-TP,也称为StARD2)、磷脂酰肌醇转运蛋白(PI-TP)和非特异性脂质转运蛋白(nsL-TP),后者可转运所有常见的二酰磷脂和胆固醇。PC-TP是一种首先从牛和鼠肝中纯化的胞质蛋白,可催化PC的膜间转运。PC-TP在肝、胎盘、睾丸、肾和心脏中的表达最高,在脑和肺组织中的表达最低。Pctp基因敲除小鼠在胆汁或肺表面活性物质中分泌PC方面没有缺陷,胆汁和表面活性物质的脂质含量和组成均正常。作者得出结论,PC-TP在从内质网(PC合成部位)到肝细胞小管膜转运PC的过程中没有发挥主要作用。编码PC-TP的基因位于人类染色体17q21-q24上。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    PC-TP 抗体 (LB-6) 参考文献:

    1. 没有磷脂酰胆碱转运蛋白的小鼠在将磷脂酰胆碱分泌到胆汁或肺气孔方面没有缺陷。  |  van Helvoort, A., et al. 1999. Proc Natl Acad Sci U S A. 96: 11501-6. PMID: 10500206
    2. 人磷脂酰胆碱转移蛋白的克隆, 组织特异性表达, 基因结构和染色体定域。  |  Cohen, DE., et al. 1999. Biochim Biophys Acta. 1447: 265-70. PMID: 10542325
    3. 通过电喷雾飞行时间质谱测定非共价磷脂转移蛋白-脂质复合物的稳定性。  |  de Brouwer, AP., et al. 2002. Biochemistry. 41: 8013-8. PMID: 12069592
    4. 磷脂转移蛋白:从脂质单层到细胞。  |  Wirtz, KW. 1991. Klin Wochenschr. 69: 105-11. PMID: 2013970

    订购信息

    产品名称产品编号规格价格数量收藏夹

    PC-TP 抗体 (LB-6)

    sc-101309
    100 µg/ml
    $333.00

    Has this antibody been used for immunocytochemistry?

    Asked by: DrTara
    Thank you for your question. We have not yet tested this mouse monoclonal antibody, PC-TP (LB-6): sc-101309, for immunocytochemistry or immunohistochemistry and so this application is not recommended at this time.
    Answered by: Technical Support
    Date published: 2017-05-15

    For Western Blot, is it recommended to use denatured or non-denatured conditions with PC-TP (LB-6): sc-101309 antibody?

    Asked by: jerojero
    Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
    Answered by: Technical Support
    Date published: 2017-03-27
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    Rated 5 out of 5 by from Good for Western BlotAntibody works well for detection of PC-TP by Western Blot in human cell line K-562. -SCBT QC
    Date published: 2023-09-14
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    PC-TP 抗体 (LB-6) is rated 4.5 out of 5 by 2.
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