Oseltamivir phosphate CAS: 204255-11-8
MF: C16H28N2O4•H3PO4
MW: 410.40
An antiviral agent.

Oseltamivir phosphate (CAS 204255-11-8)

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备用名: (3R,4R,5S)-4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic Acid Ethyl Ester Phosphate; Oseltamir Phosphate
应用; Oseltamivir phosphate is an antiviral agent
CAS号码: 204255-11-8
纯度: ≥99%
分子量: 410.40
分子式: C16H28N2O4•H3PO4
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).

Oseltamivir Phosphate is an active (orally) inhibitor of the influenze virus neuraminidase and converted to the active acid metabolite in vivo. Also demonstrates antiviral drug capabilities.


参考文献

Oliyai, R., et al.: Pharm. Res., 15, 1300 (1998), Kim, C.U., et al.: Med. Chem. Res., 8, 392 (1998), Hayden, F.G., et al.: N. Engl. J. Med., 341, 1336 (1999), Treanor, J.J., et al.: J. Am. Med. Assoc., 283, 1016 (2000)

外观 :
Crystalline
物理状态 :
Solid
溶解度 :
Soluble in water (>500 mg/ml), methanol, DMSO (2 mg/ml at 25° C), and ethanol (<1 mg/ml at 25° C).
保存 :
Store at -20° C
熔点 :
197-212° C
折射率 :
n20D 1.50 (Predicted)
IC50 :
Influenza A virus: IC50 = 1.1 µM
pK值 :
pKa: 7.7 at 25° C in primary amine
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
78000
MDL 号码 :
MFCD08059548
Beilstein 注册 :
8101020
SMILES :
CCC(CC)O[[email protected]@H]1C=C(C[[email protected]@H]([[email protected]]1NC(=O)C)N)C(=O)OCC.OP(=O)(O)O

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