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nucleoporin p62 抗体 (E-4): sc-48389

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说明书
  • nucleoporin p62 抗体 E-4 是小鼠单克隆 IgG1 κ,nucleoporin p62抗体, 在16篇文献中引用,规格为200 µg/ml
  • 免疫human物种的nucleoporin p62的氨基酸401-522
  • nucleoporin p62 抗体 (E-4) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 nucleoporin p62
  • 抗nucleoporin p62抗体(E-4)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取nucleoporin p62 (E-4): sc-48389免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是nucleoporin p62 Antibody (E-4) for WB applications. 的首选辅助检测试剂,这些试剂现与nucleoporin p62 Antibody (E-4) 打包提供(请参阅下面的订购信息)。

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関連項目

核孔蛋白p62抗体(E-4)是一种小鼠单克隆IgG1 kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)检测小鼠、大鼠和人类来源的核孔蛋白p62。抗核孔蛋白p62抗体(E-4) 有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®结合物。核孔蛋白p62在核运输系统中起着至关重要的作用,促进蛋白质和RNA穿过核膜的选择性移动。核孔蛋白p62位于核孔复合体中,对于将蛋白质导入细胞核和将新合成的mRNA导出细胞核至关重要,从而确保细胞正常功能和基因表达调控。核孔蛋白p62与其他蛋白质(如核仁蛋白α和核仁蛋白β)的相互作用对于识别和对接准备导入细胞核的底物至关重要。此外,核孔蛋白p62还与核运输因子2(NTF2)相互作用,后者对于功能的完整性至关重要。核孔蛋白p62能够调节这些过程,这凸显了其在维持细胞稳态和响应各种生理信号方面的重要性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

nucleoporin p62 抗体 (E-4) 参考文献:

  1. 大鼠海马和下丘脑核孔蛋白p62的免疫组织化学研究。  |  Xie, CX., et al. 2000. Neuroreport. 11: 2965-7. PMID: 11006975
  2. 混合性结缔组织病病例中的核孔蛋白p62抗体。  |  Kraemer, DM., et al. 2003. Clin Diagn Lab Immunol. 10: 329-31. PMID: 12626463
  3. 哺乳动物核孔蛋白p62的N端结构域在间期与FXFG家族的其他核孔蛋白相互作用。  |  Stochaj, U., et al. 2006. Exp Cell Res. 312: 2490-9. PMID: 16730000
  4. OSBP相关蛋白8(ORP8)的沉默会改变巨噬细胞的转录组、核孔蛋白p62的分布和迁移能力。  |  Béaslas, O., et al. 2012. Exp Cell Res. 318: 1933-45. PMID: 22683860
  5. 原发性胆源性胆管炎患者血清中核孔蛋白p62自身抗体的检测。  |  Bauer, A. and Habior, A. 2019. Ann Lab Med. 39: 291-298. PMID: 30623621
  6. 核蛋白 p62 在 mRNA 从细胞核输出的过程中与 mRNA 直接相互作用。  |  Dargemont, C., et al. 1995. J Cell Sci. 108 (Pt 1): 257-63. PMID: 7738103
  7. 大鼠核孔蛋白p62自结合中不同结构域的作用。  |  Buss, F., et al. 1994. J Cell Sci. 107 (Pt 2): 631-8. PMID: 8207085
  8. 针对核孔蛋白p62的自身抗体是原发性胆汁性肝硬化的一种新型标志物。  |  Wesierska-Gadek, J., et al. 1996. Gastroenterology. 110: 840-7. PMID: 8608894
  9. 低等后生动物核孔复合物蛋白的序列分析:腔肠动物水螅的核孔蛋白p62。  |  Fischer, R., et al. 1997. Gene. 195: 285-93. PMID: 9305774
  10. 人类热休克因子2的三聚体结构域能够与核孔蛋白p62相互作用。  |  Yoshima, T., et al. 1997. Biochem Biophys Res Commun. 240: 228-33. PMID: 9367915

订购信息

产品名称产品编号规格价格数量收藏夹

nucleoporin p62 抗体 (E-4)

sc-48389
200 µg/ml
$316.00

nucleoporin p62 (E-4): m-IgG Fc BP-HRP 套装

sc-526747
200 µg Ab; 10 µg BP
$354.00

nucleoporin p62 (E-4): m-IgG1 BP-HRP 套装

sc-532120
200 µg Ab; 20 µg BP
$354.00

nucleoporin p62 抗体 (E-4) AC

sc-48389 AC
500 µg/ml, 25% agarose
$416.00

nucleoporin p62 抗体 (E-4) HRP

sc-48389 HRP
200 µg/ml
$316.00

nucleoporin p62 抗体 (E-4) FITC

sc-48389 FITC
200 µg/ml
$330.00

nucleoporin p62 抗体 (E-4) PE

sc-48389 PE
200 µg/ml
$343.00

nucleoporin p62 抗体 (E-4) Alexa Fluor® 488

sc-48389 AF488
200 µg/ml
$357.00

nucleoporin p62 抗体 (E-4) Alexa Fluor® 546

sc-48389 AF546
200 µg/ml
$357.00

nucleoporin p62 抗体 (E-4) Alexa Fluor® 594

sc-48389 AF594
200 µg/ml
$357.00

nucleoporin p62 抗体 (E-4) Alexa Fluor® 647

sc-48389 AF647
200 µg/ml
$357.00

nucleoporin p62 抗体 (E-4) Alexa Fluor® 680

sc-48389 AF680
200 µg/ml
$357.00

nucleoporin p62 抗体 (E-4) Alexa Fluor® 790

sc-48389 AF790
200 µg/ml
$357.00

I need to use an antibody to detect the protein in samples of monkey origin. Do you know if sc-48389: nucleoporin p62 (E-4) mouse monoclonal antibody will work?

Asked by: AbPolly
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
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Rated 5 out of 5 by from nucleoporin p62 (E-4) SAMPLEnucleoporin p62 (E-4) SAMPLE worked great for human dendritic cells
Date published: 2019-12-04
Rated 4 out of 5 by from Looked good in IHCIn a quick test for IHC in PFA fixed, frozen sections of mouse brain tissue, antibody seemed specific and looked pretty good. 1:300, Over-night, PBS .5% Triton-X.
Date published: 2018-10-06
Rated 5 out of 5 by from excellenttested on rat tissue samples in western blot and worked perfectly.
Date published: 2017-12-13
Rated 5 out of 5 by from It is a good antibodyI bought this antibody a month ago,the clear bands appeared in the experiments.
Date published: 2017-10-15
Rated 5 out of 5 by from good antibodyThis antibody is good, i got good results! It is a wonderful expriment!
Date published: 2017-10-10
Rated 4 out of 5 by from Work WellThis antibody was used to detect nucleoporin p62 in HepG2.2.15 at 1:200 dilution, the protein bands were clear, the signals were strong.
Date published: 2017-10-07
Rated 4 out of 5 by from goodi used this antibody for the detection in ovarian tissue, i think it worked very good
Date published: 2017-07-27
Rated 5 out of 5 by from goodthis antibody works well in WB in colon cell ,i really like it
Date published: 2017-06-25
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nucleoporin p62 抗体 (E-4) is rated 4.7 out of 5 by 14.
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