Date published: 2025-9-6

021-6093-6350

SCBT Portrait Logo
Seach Input

NDRG3 抗体 (H-11): sc-514561

4.5(2)
寫評論提問

说明书
  • NDRG3 抗体 H-11 是小鼠单克隆 IgG1 κ,NDRG3抗体, 在2篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的NDRG3的N-terminus的氨基酸2-26之间
  • NDRG3 抗体 (H-11) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 NDRG3
  • 抗NDRG3抗体(H-11)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取NDRG3 (H-11): sc-514561免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgGκ BP-HRP是NDRG3 Antibody (H-11) 适用于 WB 应用。 的首选辅助检测试剂,这些试剂现与NDRG3 Antibody (H-11) 打包提供(请参阅下面的订购信息)。

快捷链接

関連項目

NDRG3抗体(H-11)是一种IgG1 κ小鼠单克隆NDRG3抗体,可通过WB、IP、IF和ELISA检测小鼠、大鼠和人类来源的NDRG3蛋白。NDRG3抗体(H-11)既可以是非偶联的抗NDRG3抗体形式,也可以是多种偶联形式的抗NDRG3抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。N-myc下游调节基因(NDRG)家族由四个成员组成,包括NDRG1(也称为Drg1、RTP、rit42、Cap43和Ndr1)、NDRG2、NDRG3和NDRG4,它们具有57-65%的同源性。定位于人类染色体8q24.3的NDRG1基因在进化上是保守的,在人类、小鼠和大鼠中具有相似的调控方式。与NDRG2和NDRG3一样,NDRG1普遍表达,但在胎盘膜以及前列腺、肾脏、小肠和卵巢组织中表达最为显著。NDRG1基因的表达受多种化合物诱导,包括镍,并产生一种参与应激反应、激素反应、细胞生长和分化的蛋白质。编码NDRG3的基因定位于人类染色体20q11,主要在睾丸、前列腺和卵巢中表达,这表明其可能在精子生成中发挥作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

NDRG3 抗体 (H-11) 参考文献:

  1. ER应激反应细胞质蛋白RTP的磷酸化。  |  Agarwala, KL., et al. 2000. Biochem Biophys Res Commun. 272: 641-7. PMID: 10860807
  2. 缺氧会诱导正常细胞和恶性细胞中 43 kDa 蛋白质(PROXY-1)的表达。  |  Park, H., et al. 2000. Biochem Biophys Res Commun. 276: 321-8. PMID: 11006124
  3. 人类 NDRG 基因家族的特征:新发现的成员 NDRG4 在大脑和心脏中特异性表达。  |  Zhou, RH., et al. 2001. Genomics. 73: 86-97. PMID: 11352569
  4. 人类 NDRG3 基因的克隆和表达模式。  |  Zhao, W., et al. 2001. Biochim Biophys Acta. 1519: 134-8. PMID: 11406283
  5. 缺氧时 NDRG3 介导的乳酸信号转导  |  Park, KC., et al. 2015. BMB Rep. 48: 301-2. PMID: 25936780
  6. NDRG3 通过激活 Src 磷酸化促进结直肠癌转移。  |  Li, T., et al. 2018. Onco Targets Ther. 11: 2843-2852. PMID: 29844682
  7. NDRG3 蛋白表达与侵袭性乳腺癌患者的侵袭性生物表型和不利预后有关。  |  Kim, MC., et al. 2019. Int J Clin Exp Pathol. 12: 3886-3893. PMID: 31933778
  8. 血清 NDRG3 与甲状腺乳头状癌的关系  |  Wang, J., et al. 2022. Front Endocrinol (Lausanne). 13: 1091462. PMID: 36619553
  9. NDRG3通过促进β-catenin在慢性骨髓性白血病细胞核中的积累来调节伊马替尼的耐药性。  |  Wang, X., et al. 2023. Oncol Rep. 50: PMID: 37350410
  10. 一个在结肠上皮细胞分化过程中上调, 在结直肠肿瘤中下调的新基因。  |  van Belzen, N., et al. 1997. Lab Invest. 77: 85-92. PMID: 9251681
  11. Cap43是一种由Ni2+化合物特异性诱导的新型基因。  |  Zhou, D., et al. 1998. Cancer Res. 58: 2182-9. PMID: 9605764
  12. RTP/rit42 对肿瘤细胞生长的抑制作用及其对 p53 和 DNA 损伤的反应。  |  Kurdistani, SK., et al. 1998. Cancer Res. 58: 4439-44. PMID: 9766676

订购信息

产品名称产品编号规格价格数量收藏夹

NDRG3 抗体 (H-11)

sc-514561
200 µg/ml
$316.00

NDRG3 (H-11): m-IgG Fc BP-HRP 套装

sc-531158
200 µg Ab; 10 µg BP
$354.00

NDRG3 (H-11): m-IgGκ BP-HRP 套装

sc-524768
200 µg Ab, 40 µg BP
$354.00

NDRG3 抗体 (H-11) AC

sc-514561 AC
500 µg/ml, 25% agarose
$416.00

NDRG3 抗体 (H-11) HRP

sc-514561 HRP
200 µg/ml
$316.00

NDRG3 抗体 (H-11) FITC

sc-514561 FITC
200 µg/ml
$330.00

NDRG3 抗体 (H-11) PE

sc-514561 PE
200 µg/ml
$343.00

NDRG3 抗体 (H-11) Alexa Fluor® 488

sc-514561 AF488
200 µg/ml
$357.00

NDRG3 抗体 (H-11) Alexa Fluor® 546

sc-514561 AF546
200 µg/ml
$357.00

NDRG3 抗体 (H-11) Alexa Fluor® 594

sc-514561 AF594
200 µg/ml
$357.00

NDRG3 抗体 (H-11) Alexa Fluor® 647

sc-514561 AF647
200 µg/ml
$357.00

NDRG3 抗体 (H-11) Alexa Fluor® 680

sc-514561 AF680
200 µg/ml
$357.00

NDRG3 抗体 (H-11) Alexa Fluor® 790

sc-514561 AF790
200 µg/ml
$357.00

NDRG3 (H-11) 中和勝肽

sc-514561 P
100 µg/0.5 ml
$68.00

We're testing NDRG3 antibody (Cat #; sc-514561). Among the 2 isoforms of NDRG3 proteins in humans (i.e., NM_032013.3 (isoform a) and NM_022477.3 (isoform b)), which one is detected by sc-514561? Please tell us the peptide sequence used to generate MAb.

Asked by: Young IL
Thank you for your question. This mouse monoclonal antibody is raised against a peptide mapping between amino acids 2-26 at the N-terminus of NDRG3 of human origin, Uniprot accession number Q9UGV2.
Answered by: Technical Support Europe
Date published: 2019-03-25

What application is the blocking peptide sc-514561 P appropriate for?

Asked by: Cweed
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_8, d_30, h_9CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_514561, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 115ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by from Anti-NDRG3 per analisi in western blotL'anticorpo è stato testato in linee tumorali di mammella (MCF-7 e MDA-231). L'anticorpo primario è stato preparato in BSA 5% alla diluizione 1:1000, il secondario sempre in BSA 5% ma alla diluizione 1:2000. Il segnale ottenuto è pulito, con un'unica banda del perso molecolare atteso.
Date published: 2023-10-04
Rated 5 out of 5 by from Clean antibody for Western blot detection of NDRG3Antibody detects NDRG3 by Western blot in human cell lines Raji (left) and LnCAP (right) -SCBT QC
Date published: 2023-09-14
  • y_2025, m_8, d_30, h_9
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_zh_CN, sid_514561, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 7ms
  • REVIEWS, PRODUCT
NDRG3 抗体 (H-11) is rated 4.5 out of 5 by 2.
  • y_2025, m_8, d_30, h_9
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_zh_CN, sid_514561, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 102ms
  • REVIEWS, PRODUCT