Date published: 2025-9-8
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N-cadherin Antibody (D-4) - Immunohistochemistry - Image 114236
N-cadherin 抗体 (D-4): sc-8424. 福尔马林固定, 石蜡包埋的人体肝脏组织的免疫过氧化物酶染色, 低倍镜下显示七细胞膜染色. 瑞典人类蛋白质图谱 (HPA) 计划友情提供.
N-cadherin 抗体 (D-4): sc-8424. 福尔马林固定, 石蜡包埋的人体肝脏组织的免疫过氧化物酶染色, 低倍镜下显示七细胞膜染色. 瑞典人类蛋白质图谱 (HPA) 计划友情提供.

N-cadherin 抗体 (D-4): sc-8424

4.1(10)
寫評論提問

说明书
  • N-cadherin 抗体 D-4 是小鼠单克隆 IgG1 κ，N-cadherin抗体, 在120篇文献中引用，规格为200 µg/ml
  • 针对氨基酸450-512，在N-cadherin的细胞外区域，human起源
  • N-cadherin 抗体 (D-4) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA，检测mouse, rat 和human 来源的 N-cadherin; 也和以下物种反应，包括： 和 equine and canine
  • 抗N-cadherin抗体（D-4）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取N-cadherin (D-4): sc-8424的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP 和 m-IgG1 BP-HRP 是 N-cadherin 抗体 (D-4) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与N-cadherin 抗体 (D-4) 组合成套装提供。 (请参阅下面的订购信息)。

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相关产品
描述
基因信息
蛋白序列
说明书与实验方案
研究信息

関連項目

此外 Cadherin 抗体 包括 cadherin-16, cadherin-19, cadherin-23, E-cadherin, EY-cadherin, K-cadherin, LI-cadherin, M-cadherin, N-cadherin和OB-cadherin

N-cadherin 抗体（D-4）是一种小鼠单克隆 IgG1 kappa 轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）、免疫组织化学和酶联免疫吸附测定（ELISA）检测小鼠、大鼠和人类来源的 N-cadherin。N-cadherin 单克隆抗体（D-4）有非结合型和多种结合型，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种 Alexa Fluor® 结合物。N-cadherin，也称为CD325或CDH2，在细胞粘附中起着至关重要的作用，对于维持组织完整性和促进发育过程中的形态发生过程至关重要。N-cadherin主要位于细胞膜上，形成连接相邻细胞的粘附连接，从而促进组织结构的稳定性。这种定位使N-cadherin能够与细胞骨架和其他信号分子相互作用，影响细胞行为和通信。N-cadherin的细胞外结构域包含五个同源重复序列，可促进同源结合，而细胞内结构域则与β-catenin等细胞质蛋白相互作用，与肌动蛋白细胞骨架相连，调节细胞运动和组织结构。了解N-cadherin的功能和定位有助于阐明其在各种生理过程中的作用，以及其在癌症等疾病中的影响，因为N-cadherin的表达改变会导致细胞迁移和转移增加。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

N-cadherin 抗体 (D-4)

sc-8424
200 µg/ml
$316.00

N-cadherin (D-4): m-IgG Fc BP-HRP 套装

sc-526524
200 µg Ab; 10 µg BP
$354.00

N-cadherin (D-4): m-IgG1 BP-HRP 套装

sc-531897
200 µg Ab; 20 µg BP
$354.00

N-cadherin 抗体 (D-4) AC

sc-8424 AC
500 µg/ml, 25% agarose
$416.00

N-cadherin 抗体 (D-4) HRP

sc-8424 HRP
200 µg/ml
$316.00

N-cadherin 抗体 (D-4) FITC

sc-8424 FITC
200 µg/ml
$330.00

N-cadherin 抗体 (D-4) PE

sc-8424 PE
200 µg/ml
$343.00

N-cadherin 抗体 (D-4) Alexa Fluor® 488

sc-8424 AF488
200 µg/ml
$357.00

N-cadherin 抗体 (D-4) Alexa Fluor® 546

sc-8424 AF546
200 µg/ml
$357.00

N-cadherin 抗体 (D-4) Alexa Fluor® 594

sc-8424 AF594
200 µg/ml
$357.00

N-cadherin 抗体 (D-4) Alexa Fluor® 647

sc-8424 AF647
200 µg/ml
$357.00

N-cadherin 抗体 (D-4) Alexa Fluor® 680

sc-8424 AF680
200 µg/ml
$357.00

N-cadherin 抗体 (D-4) Alexa Fluor® 790

sc-8424 AF790
200 µg/ml
$357.00

Can N-cadherin Antibody (D-4): sc-8424 be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: jenni
Thank you for your question. Yes, N-cadherin Antibody (D-4): sc-8424 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support 14
Date published: 2024-08-22
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Rated 4 out of 5 by from Good productIt is good antibodies in WB. It works in dilution 1:1000.
Date published: 2018-07-14
Rated 5 out of 5 by from UPENNGα 12 Antibody is very good. The band is very stronger.
Date published: 2018-04-19
Rated 1 out of 5 by from Antibody does not work for IHC-PI purchased this antibody based on very nice images on the website showing specifically localization of NCAD in IHC-P. I tested the antibody using multiple techniques and tissue types with no staining. I reported the problems to the company and they kindly provided a replacement vial. Unfortunately the replacement did not work either again using multiple techniques and tissue types. While this antibody may have previously worked well in IHC-P, the current product being provided does not work for IHC-P.
Date published: 2018-02-03
Rated 1 out of 5 by from Almost no detectable in SK-hep1, RPMI8226 cell linAlmost no detectable in SK-hep1 and RPMI8226 cell lines. So I used femto. I only could detect strong background.
Date published: 2017-12-06
Rated 5 out of 5 by from Outstanding IHC !!Very clear and specific IHC staining data; also strong WB
Date published: 2017-01-11
Rated 5 out of 5 by from Very Versatile AntibodyThis antibody is well-cited for a variety of applications including WB, IP, IF, and even IHC and ELISA. Strong, clear signal with little to no background. Works well in a variety of species including mouse, rat, equine, bovine, and human samples.
Date published: 2016-12-29
Rated 5 out of 5 by from Worked with fusion protien by WB with someWorked with fusion protien by WB with some background -SCBT QC
Date published: 2015-03-18
Rated 5 out of 5 by from Very good antibody for IHC in paraffinVery good antibody for IHC in paraffin-embedded human sections. -SCBT QC
Date published: 2015-02-03
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N-cadherin抗体 (D-4) is rated 4.1 out of 5 by 10.
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