(-)-MK 801 maleate (CAS 77086-19-2)

物理状态 :

Solid

溶解度 :

Soluble in water (25 mM), DMSO (68 mg/ml at 25 °C), and ethanol (50 mM).

保存 :

Store at 4° C

熔点 :

203-205° C

折射率 :

n²⁰_D 1.63 (Predicted)

光学活性 :

α25/D -118°, c = 0.64 in ethanol; α25/D -117.7°, c = 1 in methanol

IC50 :

[3H]TCP binding: IC₅₀ = 9 nM (hippocampus); N-methyl-D-aspartate-induced [3H]norepinephrine (NE) release: IC₅₀ = 20 nM; NMDA: IC₅₀ = 37.2 nM; Microglial TNF-α output: EC₅₀50 = 400 µM (BV-2 cells)

德国水公害等级 :

3

PubChem CID :

Merck 索引 :

14: 3386

MDL 号码 :

MFCD00082466

SMILES :

C[C@]12C3=CC=CC=C3C[C@H](N1)C4=CC=CC=C24.C(=C\\C(=O)O)\\C(=O)O