MIG Antibody (ZZ-6): sc-74227

MIG Antibody (ZZ-6) is a mouse monoclonal IgG1 antibody that detects MIG in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). MIG, also known as chemokine (C-X-C motif) ligand 9 (CXCL9), plays a crucial role in immune response by mediating T cell trafficking and exhibiting anti-tumor effects, which are vital for the body′s ability to combat cancer and infections. This secreted chemokine is primarily located in the extracellular space, where MIG interacts with the Gα i protein-coupled receptor CXCR3, facilitating the migration of immune cells to sites of inflammation or tumor growth. MIG (ZZ-6) antibody helps researchers study how MIG inhibits angiogenesis and blocks responses induced by other inflammatory mediators, such as platelet activating factor and leukotriene B4, underscoring MIG′s importance in regulating immune responses and maintaining tissue homeostasis. Elevated levels of MIG have been associated with various pathological conditions, including ocular sarcoidosis, where MIG serum concentration correlates with disease activity, highlighting MIG′s potential as a biomarker for monitoring inflammatory diseases. With MIG′s multifaceted roles in immune regulation, anti-MIG antibody (ZZ-6) serves as an essential tool for scientists studying immune mechanisms and cancer biology.

The preferred MIG antibody is MIG Antibody (A-9): sc-514138.