Date published: 2025-9-9

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LHX6 抗体 (A-9): sc-271433

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说明书
  • LHX6 抗体 A-9 是小鼠单克隆 IgG2a κ,LHX6抗体, 在24篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列1-75位于human物种的LHX6的N-terminus
  • LHX6 抗体 (A-9) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 LHX6
  • 抗LHX6抗体(A-9)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于ChIP的TransCruz试剂(sc-271433 X, 200 µg/0.1 ml)
  • 关于如何获取LHX6 (A-9): sc-271433免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP是LHX6 Antibody (A-9) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与LHX6 Antibody (A-9) 搭配使用(请参阅下面的订购信息)。

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関連項目

LHX6抗体(A-9)是一种IgG2a κ小鼠单克隆LHX6抗体,可通过WB、IP、IF和ELISA检测小鼠、大鼠和人类来源的LHX6蛋白。LHX6抗体(A-9)既有非偶联的抗LHX6抗体形式,也有多种偶联形式的抗LHX6抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。在发育过程中,遗传上不同的运动神经元亚型表达独特的LIM型同源结构域因子组合,这些因子调节细胞迁移并引导运动轴突建立轴突轨迹中二元选择的保真度。LIM基因家族编码一组携带LIM结构域的蛋白质,LIM结构域是一种独特的富含半胱氨酸的锌结合基序。LHX6(LIM同源盒6),也称为LHX6.1,是一种含有两个LIM锌结合结构域和一个同源盒DNA结合结构域的363个氨基酸的核蛋白。LHX6特异性表达于大脑中,被认为是一种转录调节因子,可能在淋巴细胞和神经细胞的发育和分化中发挥作用。此外,LHX6在头颈部癌中高度甲基化,可能是一种新的肿瘤标志物。由于选择性剪接事件,存在两种LHX6异构体,分别命名为LHX6.1A和LHX6.1B。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

LHX6 抗体 (A-9) 参考文献:

  1. 脑区特异性基因产物Lhx6.1通过串联的LIM-domains与Ldb1相互作用。  |  Kimura, N., et al. 1999. J Biochem. 126: 180-7. PMID: 10393337
  2. 基于细菌人工染色体的中枢神经系统基因表达图谱。  |  Gong, S., et al. 2003. Nature. 425: 917-25. PMID: 14586460
  3. Lhx6调控大脑皮层中间神经元从腹侧端脑的迁移,但并不指定它们的GABA表型。  |  Alifragis, P., et al. 2004. J Neurosci. 24: 5643-8. PMID: 15201337
  4. Lhx6划定了一条从杏仁核到下丘脑的先天生殖行为介导途径。  |  Choi, GB., et al. 2005. Neuron. 46: 647-60. PMID: 15944132
  5. LHX6 是头颈部癌中一种敏感的甲基化标记物。  |  Estécio, MR., et al. 2006. Oncogene. 25: 5018-26. PMID: 16732332
  6. 大脑皮层中间神经元亚型的正常迁移和分化需要Lhx6的活性。  |  Liodis, P., et al. 2007. J Neurosci. 27: 3078-89. PMID: 17376969
  7. NKX2.1通过激活Lhx6决定皮质中间神经元的命运  |  Du, T., et al. 2008. Development. 135: 1559-67. PMID: 18339674
  8. Lhx6和Lhx7是一个新的LIM同源模编码基因亚家族,其表达和调控表明它们在哺乳动物头部发育中发挥作用。  |  Grigoriou, M., et al. 1998. Development. 125: 2063-74. PMID: 9570771

订购信息

产品名称产品编号规格价格数量收藏夹

LHX6 抗体 (A-9)

sc-271433
200 µg/ml
$316.00

LHX6 (A-9): m-IgG Fc BP-HRP 套装

sc-525807
200 µg Ab; 10 µg BP
$354.00

LHX6 抗体 (A-9) X

sc-271433 X
200 µg/0.1 ml
$316.00

LHX6 抗体 (A-9) AC

sc-271433 AC
500 µg/ml, 25% agarose
$416.00

LHX6 抗体 (A-9) HRP

sc-271433 HRP
200 µg/ml
$316.00

LHX6 抗体 (A-9) FITC

sc-271433 FITC
200 µg/ml
$330.00

LHX6 抗体 (A-9) PE

sc-271433 PE
200 µg/ml
$343.00

LHX6 抗体 (A-9) Alexa Fluor® 488

sc-271433 AF488
200 µg/ml
$357.00

LHX6 抗体 (A-9) Alexa Fluor® 546

sc-271433 AF546
200 µg/ml
$357.00

LHX6 抗体 (A-9) Alexa Fluor® 594

sc-271433 AF594
200 µg/ml
$357.00

LHX6 抗体 (A-9) Alexa Fluor® 647

sc-271433 AF647
200 µg/ml
$357.00

LHX6 抗体 (A-9) Alexa Fluor® 680

sc-271433 AF680
200 µg/ml
$357.00

LHX6 抗体 (A-9) Alexa Fluor® 790

sc-271433 AF790
200 µg/ml
$357.00

When should the TransCruz reagent sc-271433 X be used instead of the standard form sc-271433?

Asked by: jenniferc
Thank you for your question. We recommend using the TransCruz reagent form when performing ChIP or GelShift assays. This form can also be used in other applications such as Western Blot or IHC, but the dilution should be adjusted by a factor of 10 to account for the higher original concentration.
Answered by: Technical Support 3
Date published: 2017-01-10
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Rated 5 out of 5 by from Rat Medial Ganglionic Eminence Cell SmearThis antibody works well on medial ganglionic eminence (MGE) cells from rat. Few vendors carry this antibody. I am happy I was able to find it and have success with it.
Date published: 2017-08-08
Rated 5 out of 5 by from Highly specific WBNice product for western blot applications; strong signal with low background
Date published: 2017-01-13
Rated 5 out of 5 by from Great for Western blotThe LHX6 Antibody (A-9) is excellent for Western blot applications, showing clear single band with minimal background.
Date published: 2016-12-21
Rated 5 out of 5 by from We have used the LHX6 (AWe have used the LHX6 (A-9) antibody and it seems to be working really well.
Date published: 2015-09-04
Rated 5 out of 5 by from Used in IF and got good stainingUsed in IF and got good staining.
Date published: 2015-08-28
Rated 5 out of 5 by from Good specificity in WB in DU 145Good specificity in WB in DU 145, IMR-32 and HeLa nuclear extacts. -SCBT QC
Date published: 2015-06-29
Rated 5 out of 5 by from Band of interest detected in WB in UBand of interest detected in WB in U-87 MG whole cell lysate. -SCBT QC
Date published: 2015-05-08
Rated 5 out of 5 by from StrongStrong, clear band detected in WB in K-562 and T-47D whole cell lysates. -SCBT QC
Date published: 2014-08-17
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LHX6 抗体 (A-9) is rated 5.0 out of 5 by 8.
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