Leflunomide 3-Isomer CAS: 61643-23-0
MF: C12H9F3N2O2
MW: 270.21
A Leflunomide analogue.

Leflunomide 3-Isomer (CAS 61643-23-0)

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应用; A Leflunomide analogue
CAS号码: 61643-23-0
分子量: 270.21
分子式: C12H9F3N2O2
* 参考分析证明 大量特定数据 (包括水 含量).
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Leflunomide 3-Isomer is a Leflunomide (sc-202209) analogue, which inhibits virus replication. Studies indicate that Leflunomide displays immunomodulating properties and anti-inflammatory activities, which may be due to its ability to inhibit DNA synthesis in synovial cells and PAF production in macrophages. Leflunomide is an isoxazol derivative, which displays inhibitory effects against IL-2 induced T-cell production, which were stimulated with anti-CD3 plus PMA or anti-CD28 plus PMA. Furthermore, Leflunomide 3-Isomer can be used as a tool to study the mechanism of immunosuppression.


参考文献

1. Chong, A.S., et al. 1993. Transplant. Proc. 25: 747-749. PMID: 8438466
2. Chong, A.S., et al. 1993. Transplantation. 55: 1361-1366. PMID: 8390735
3. Ju, D.W., et al. 1994. Yao Xue Xue Bao. 29: 90-94. PMID: 8042517

外观 :
Powder
物理状态 :
Solid
保存 :
Store at 4° C
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
7314718
SMILES :
CC1=C(C=NO1)C(=O)NC2=CC=CC(=C2)C(F)(F)F

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