L-alpha-Phosphatidylinositol-3,4,5-trisphosphate, Dipalmitoyl-, Heptaammonium Salt MF: C41H75O22P4•7NH4
MW: 1170.2
A Ca2+-insensitive PKCδ, PKCε, and PKCη activator.
  1. 首页
  2. 化学品
  3. Protein-Interacting Inhibitors, Activators & Substrates
  4. Protein激活剂
  5. PKC η激活剂
  6. L-α-Phosphatidylinositol-3,4,5-trisphosphate, Dipalmitoyl-, Heptaammonium Salt

L-α-Phosphatidylinositol-3,4,5-trisphosphate, Dipalmitoyl-, Heptaammonium Salt

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 112ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
(0)
写一个评价 提问
查看产品引用文献(1)
备用名: PI-3,4,5-P3, 7NH4, PIP3, Dipalmitoyl-
应用； L-α-Phosphatidylinositol-3,4,5-trisphosphate, Dipalmitoyl-, Heptaammonium Salt is a Ca2+-insensitive PKCδ, PKCε, and PKCη ac
纯度: ≥98%
分子量: 1170.2
分子式: C41H75O22P4•7NH4
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).

快捷链接

点击图片或放大按钮来放大

PI-3,4,5-P3, 7NH4, PIP3, Dipalmitoyl- activates Ca2+-insensitive PKCδ, PKCε, and PKCη isozymes. Binds to the general receptor for phosphoinositide-1 (GRP1) protein through a plekstrin homology (PH) domain. Has also been shown to produce actin reorganization, membrane ruffling and increase motility of NIH/3T3 cells.


参考文献

1. Toker, A., et al., 1994. Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3. The Journal of biological chemistry. 269(51): 32358-67. PMID: 7798235
2. Ireton, K., et al., 1996. A role for phosphoinositide 3-kinase in bacterial invasion. Science (New York, N.Y.). 274(5288): 780-2. PMID: 8864117
3. Derman, M P., et al., 1997. The lipid products of phosphoinositide 3-kinase increase cell motility through protein kinase C. The Journal of biological chemistry. 272(10): 6465-70. PMID: 9045671
4. Klarlund, J K., et al., 1997. Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains. Science (New York, N.Y.). 275(5308): 1927-30. PMID: 9072969

物理状态 :
Solid
溶解度 :
Soluble in DMSO (1 mg/ml).
保存 :
Store at -20° C
沸点 :
>300° C
折射率 :
n20D ~1.53 (Predicted)
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
16760614
SMILES :
[N+].[N+].[N+].[N+].[N+].[N+].[N+].CCCCCCCCCCCCCCCC(=O)OCC(CO[P](=O)([O-])O[[email protected]]1[[email protected]](O)[[email protected]@H](O[P](=O)([O-])[O-])[[email protected]](O[P](=O)([O-])[O-])[[email protected]@H](O[P](=O)([O-])[O-])[[email protected]]1O)OC(=O)CCCCCCCCCCCCCCC

下载SDS

分析证明书

在PDF文件上阅读，打印和批注，Adobe阅读器是必须的

L-alpha-Phosphatidylinositol-3,4,5-trisphosphate, Dipalmitoyl-, Heptaammonium Salt  产品相关文献索引

看其他用户如何应用L-alpha-Phosphatidylinositol-3,4,5-trisphosphate, Dipalmitoyl-, Heptaammonium Salt.点击进入浏览PubMed条目 .

引用1 - 1 的 1

PMID: # 20617170  Fausther-Bovendo H et al. 2010. PLoS Pathog. 6: :e1000975.

引用1 - 1 的 1
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 90ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 6ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

圣克鲁斯生物技术在生物医药研究市场的产品开发方面处于世界领先地位。欢迎 致电我们的免费电话(021) 800-820-8626。 版权 ©, 2007-2021圣克鲁斯生物技术。版权所有。“Santa Cruz Biotechnology”，圣克鲁斯生物技 术的 商标，“Santa Cruz Animal Health”，“San Juan Ranch”，“Supplement of Champions”，San Juan Ranch的商标，“Ultracruz”，“Chemcruz”，“Immunocruz”，“Exactacruz”和“EZ Touch”都是圣克鲁斯生物技术的注册商标。所有的商标都归其各自拥有者所有。