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Keratin 81 抗体 (36-Z): sc-100929

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说明书
  • Keratin 81 抗体 36-Z 是小鼠单克隆 IgG2b κ,Keratin 81抗体, 在7篇文献中引用,规格为100 µg/ml
  • 免疫human物种的重组Keratin 81
  • 推荐用于 human 来源的Keratin 81 WB, IP, IF, IHC(P) 和 ELISA检测
  • 关于如何获取Keratin 81 (36-Z): sc-100929免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG2b BP-HRP 是Keratin 81 抗体 (36-Z) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与Keratin 81 抗体 (36-Z) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

角蛋白81抗体(36-Z)是一种小鼠单克隆IgG2b kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、石蜡包埋切片免疫组织化学(IHCP)和酶联免疫吸附测定(ELISA)检测人类角蛋白81蛋白。抗角蛋白81抗体(36-Z)以非结合形式提供。角蛋白81,也称为KRTHB1、MLN137、HB1或Hb-1,是一种由505个氨基酸组成的II型毛发角蛋白,主要在生长毛发的皮质中表达。角蛋白81在头发纤维的结构完整性和弹性方面发挥着至关重要的作用,因为角蛋白81是异四聚体结构的一部分,该结构包括两种I型和两种II型角蛋白,对于头发和指甲纤维的组装至关重要。角蛋白81的正常功能至关重要,因为编码角蛋白81的基因突变可导致毛滴虫病,这是一种常染色体显性遗传的毛发疾病,其特征是头皮、眉毛和睫毛上出现易断的稀疏毛发。角蛋白多基因家族包括角蛋白81,分为"软"上皮细胞角蛋白和"硬"毛发角蛋白,前者有助于上皮组织的形成和分层。角蛋白81单克隆抗体(36-Z)可在各种应用中有效检测这种重要蛋白质,因此角蛋白81(36-Z)抗体成为研究毛发生物学和相关疾病的研究人员的宝贵工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Keratin 81 抗体 (36-Z) 参考文献:

  1. 含有 II 型毛发角蛋白基因结构域的 300 kbp 人类 DNA 区域的特征。  |  Rogers, MA., et al. 2000. J Invest Dermatol. 114: 464-72. PMID: 10692104
  2. 定义角蛋白中间丝结构, 功能和调节的 '硬 '和 '软 '原则。  |  Coulombe, PA. and Omary, MB. 2002. Curr Opin Cell Biol. 14: 110-22. PMID: 11792552
  3. 人类毛囊角蛋白。  |  Langbein, L. and Schweizer, J. 2005. Int Rev Cytol. 243: 1-78. PMID: 15797458
  4. 哺乳动物角蛋白的新共识命名法。  |  Schweizer, J., et al. 2006. J Cell Biol. 174: 169-74. PMID: 16831889
  5. 人类 I 型和 II 型毛发角蛋白基因的序列数据和染色体定位。  |  Rogers, MA., et al. 1995. Exp Cell Res. 220: 357-62. PMID: 7556444
  6. 与遗传性毛发疾病 monilethrix 有关的 II 型毛发皮质角蛋白 hHb1 的新突变。  |  Winter, H., et al. 1997. Hum Genet. 101: 165-9. PMID: 9402962
  7. 人类毛发特异性角蛋白基因的定性和染色体定域以及在毛发生长周期中的比较表达。  |  Bowden, PE., et al. 1998. J Invest Dermatol. 110: 158-64. PMID: 9457912
  8. 一种与 II 型毛发角蛋白 hHb1 的螺旋终止基序中的新型突变 Glu402Lys 相关的可变单发表型。  |  Winter, H., et al. 1998. J Invest Dermatol. 111: 169-72. PMID: 9665406

订购信息

产品名称产品编号规格价格数量收藏夹

Keratin 81 抗体 (36-Z)

sc-100929
100 µg/ml
$333.00

Keratin 81 (36-Z): m-IgG2b BP-HRP 套装

sc-548473
100 µg Ab; 10 µg BP
$354.00

What is the epitope? is it monoclonal or polyclonal?

Asked by: Diane
Thank you for your question. Keratin 81 (36-Z): sc-100929 monoclonal antibody was raised against amino acids 1-203 of recombinant Keratin 81 of human origin (accession # Q14533).
Answered by: Technical Support
Date published: 2018-12-05

Can Keratin 81 (36-Z): sc-100929 be frozen?

Asked by: jenniferc
No. The antibody solution contains gelatin. When the gelatin is frozen the antibody precipitates out of solution. However, if an antibody’s datasheet says that the antibody should be stored frozen, then the antibody can be frozen, as these antibodies do not contain gelatin.
Answered by: Technical Support 7
Date published: 2017-01-24
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Rated 5 out of 5 by from Excellent choice for IHC(P)If you are looking for a strong Keratin 81 antibody, this is the one! It's really strong for IHC, but also really good for WB and IF. Highly recommend it!
Date published: 2016-12-30
Rated 5 out of 5 by from IHC publishable data with human squamous cellIHC publishable data with human squamous cell, bronchiolar epithelium, and lung - SCBT Publication Review
Date published: 2015-04-13
Rated 5 out of 5 by from Strong band in WB in HepG2 whole cell lysateStrong band in WB in HepG2 whole cell lysate. -SCBT QC
Date published: 2015-04-12
Rated 5 out of 5 by from Excellent immunoperoxidase cytoplasmic stainingExcellent immunoperoxidase cytoplasmic staining in formalin-fixed, paraffin-embedded human esophagus tissue. -SCBT QC
Date published: 2014-02-23
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Keratin 81 抗体 (36-Z) is rated 5.0 out of 5 by 4.
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