Date published: 2025-9-8

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ITF-2/TCF4 抗体 (367.2): sc-101095

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说明书
  • ITF-2/TCF4抗体(367.2)是小鼠单克隆IgG1 κ, 在2篇文献中引用,规格为100 µg/ml
  • 免疫human物种的重组ITF-2
  • 推荐用于 mouse, rat 和 human 来源的ITF-2 WB, IP 和 ELISA检测
  • 目前,我们还没有完成ITF-2/TCF4 抗体 (367.2)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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ITF-2抗体(367.2)是一种小鼠单克隆IgG1抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)和酶联免疫吸附测定(ELISA)等方法检测小鼠、大鼠和人类样本中的免疫球蛋白转录因子2(ITF-2)。ITF-2通过与免疫球蛋白增强子Mu-E5/KE5-motif和SSTR2-INR中的Ephrussi-box(E-box)元件等特定DNA序列结合,在基因表达调控中发挥着关键作用,尤其是在肌肉发育方面。抗ITF-2抗体(367.2)可识别激活肌肉特异性基因所必需的转录因子,该因子能够与肌球蛋白和MyoD等其他肌源性因子形成同源或异源寡聚体。ITF-2在包括成人心脏、大脑、胎盘和骨骼肌在内的各种组织中的表达表明其在细胞过程中的普遍作用。此外,ITF-2的可选剪接异构体可对转录进行细微调节,从而激活或抑制目标基因,这对于维持正常的肌肉功能和发育至关重要。ITF-2单克隆抗体(367.2)是研究肌肉生物学和转录调控的研究人员的重要工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

ITF-2/TCF4 抗体 (367.2)

sc-101095
100 µg/ml
$333.00

I am looking for anti-ITF-2 (N-16; Santa Cruz) or anti-ITF-2 (K-12; Santa Cruz) primary antibodies but on searching these N-16 and K-12 antibodies I am getting ITF2 (367.2) is it same

Asked by: shariq
Thank you for your question. The two antibodies you are searching for are polyclonal antibodies that are no longer available. We currently offer mouse monoclonal antibodies against ITF-2. Please contact our Technical Service Department for help in choosing the best antibody for your research.
Answered by: Technical Support
Date published: 2020-06-03

For Western Blot, is it recommended to use denatured or non-denatured conditions with ITF-2 (367.2): sc-101095 antibody?

Asked by: TinTin
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 1 out of 5 by from Antibody can NOT distinguish between FL & TR TCF4Unlike SantaCruz's goat anti-ITf2 (N16) [discontinued], this monoclonal antibody failed to distinguish between truncated and full length TCF4 protein lysates from mouse frontal cortex tissue. It produced what seems to be a false band in the tr/tr lane at the same size as the fl/fl. The kDa difference should be around 7-10kda, but nothing is seen. Personally, I wouldn't recommend this product for TCF4 expression.
Date published: 2018-07-24
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ITF-2/TCF4 抗体 (367.2) is rated 2.0 out of 5 by 2.
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