IgG Fab fragment Antibody (4A11): sc-51642

IgG Fab fragment Antibody (4A11) is a mouse monoclonal IgG2b kappa light chain antibody that detects the IgG Fab fragment protein of human origin by western blotting (WB). Anti-IgG Fab fragment antibody (4A11) is available as a non-conjugated format. IgG Fab fragment (4A11) antibody recognizes a crucial component involved in immune response, specifically in antigen binding. IgG Fab fragment originates from the IgG molecule, composed of two heavy chains and two light chains, forming distinct regions that facilitate antigen recognition. The Fab region enables specific binding to antigens, allowing immune system targeting and pathogen neutralization. IgG Fab fragments bind to diverse antigens from viruses, bacteria, and fungi, highlighting their significance in adaptive immunity. Structural integrity of Fab fragments maintains binding affinity and specificity, directly impacting immune response effectiveness. Anti-IgG Fab fragment antibody (4A11) enables researchers to investigate immune recognition mechanisms and antibody-mediated protection against infections.

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IgG Fab fragment Antibody (4A11) References:

1. Cloning and molecular characterization of a human recombinant IgG Fab binding to the Tat protein of human immunodeficiency virus type 1 (HIV-1) derived from the repertoire of a seronegative patient.  |  Mancini, N., et al. 2006. Mol Immunol. 43: 1363-9. PMID: 16199090
2. F(ab')2 antibody fragments against Trypanosoma cruzi calreticulin inhibit its interaction with the first component of human complement.  |  Aguilar, L., et al. 2005. Biol Res. 38: 187-95. PMID: 16238097
3. Effects of IgG and its F(ab')2 fragments of some patients with idiopathic thrombocytopenic purpura on platelet aggregation.  |  Chu, XX., et al. 2006. Eur J Haematol. 76: 153-9. PMID: 16405437
4. Site-specific conjugation of bifunctional chelator BAT to mouse IgG1 Fab' fragment.  |  Li, J., et al. 2006. Acta Pharmacol Sin. 27: 237-41. PMID: 16412275
5. Investigation of conformational changes induced by binding of pancreatic RNase to anti-RNase IgG derived Fab monomer using optical procedures.  |  Younus, H., et al. 2006. Biochemistry (Mosc). 71: 218-21. PMID: 16489928
6. Comparison between therapeutic antitoxin F(ab)2 fractionated with ammonium sulfate and caprylic acid.  |  Redwan, el-RM. 2006. J Immunoassay Immunochem. 27: 319-29. PMID: 16981645
7. Effector mechanisms in myasthenia gravis: end-plate function after passive transfer of IgG, Fab, and F(ab')2 hybrid molecules.  |  Sterz, R., et al. 1986. Muscle Nerve. 9: 306-12. PMID: 2423869
8. Comparison of IgG Fab conjugates for bluetongue antibody detection by the ELISA.  |  Snydelaar Hardwicke, AC. and Carlson, JH. 1987. Rev Latinoam Microbiol. 29: 153-5. PMID: 2830650
9. [Preparation and comparative evaluation of peroxidase conjugates based on pure antibodies and the IgG Fab fragment].  |  Marennikova, SS., et al. 1982. Zh Mikrobiol Epidemiol Immunobiol. 99-103. PMID: 6755989

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-IgG Fab fragment Antibody (4A11) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-IgG Fab fragment Antibody (4A11) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

IgG Fab fragment Antibody (4A11) Specifications

Alternate Product Name: IgG Fab fragment

Product Clone Name: 4A11

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b

Amino Acids:

Epitope Target: the Fab fragment of IgG

Epitope Species: human

Product Reactivity/Detection: Fab fragments (regardless of light chain type)

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB

Vialing Information: Each vial contains 100 µg IgG_2b in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for IgG Fab fragment Antibody (4A11): N/A