Date published: 2025-9-9

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HYAL1 抗体 (1D10): sc-101340

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说明书
  • HYAL1 抗体 1D10 是小鼠单克隆 IgG1 κ,HYAL1抗体, 在8篇文献中引用,规格为200 µg/ml
  • 免疫human物种的HYAL1的氨基酸1-366
  • HYAL1 抗体 (1D10) 推荐用于 WB, IP, IF 和 IHC(P),检测mouse, rat, human 和hamster 来源的 HYAL1; 不会与 HYAL2 or HYAL3产生交联反应
  • 抗HYAL1抗体(1D10)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取HYAL1 (1D10): sc-101340免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 HYAL1 抗体 (1D10) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与HYAL1 抗体 (1D10) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

HYAL1抗体(1D10)是一种IgG1 κ小鼠单克隆HYAL1抗体,可通过蛋白质印迹法(WB)、免疫沉淀法(IP)、免疫荧光法(IF)和免疫组织化学法(IHC(P))检测到小鼠、大鼠、人类和仓鼠来源的HYAL1蛋白。HYAL1抗体(1D10)既有非偶联的抗HYAL1抗体形式,也有多种偶联形式的抗HYAL1抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。透明质酸酶(HAases或HYALs)是一类溶酶体酶,对于多种毒液中存在的细菌感染和毒素的扩散至关重要。HYALs也可能参与癌症的进展。在人类中,已经鉴定出六种HYAL蛋白。大多数HYAL蛋白会降解存在于体液、组织和脊椎动物组织的细胞外基质中的透明质酸(HA)。HA使组织保持水分,维持渗透平衡,并促进细胞增殖、分化和转移。HA也是软骨和其他组织的重要结构成分,并充当关节中的润滑剂。HYAL1是一种由435个氨基酸组成的透明质酸酶,在多种组织中表达,特别是在血清中表达,但在大脑中不表达。HYAL1将HA降解为刺激血管生成的片段。HYAL1在各种癌细胞中的表达可能在肿瘤生长和进展的调控中发挥作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

HYAL1 抗体 (1D10) 参考文献:

  1. 小鼠透明质酸酶基因区域的特征显示了 Hyal1 与下游基因 Fus2 和 Hyal3 的复杂组织和共转录。  |  Shuttleworth, TL., et al. 2002. J Biol Chem. 277: 23008-18. PMID: 11929860
  2. 头颈部肿瘤中肿瘤标志物透明质酸和透明质酸酶(HYAL1)的表达。  |  Franzmann, EJ., et al. 2003. Int J Cancer. 106: 438-45. PMID: 12845686
  3. 透明质酸, 透明质酸酶(HYAL-1), CD44v6 和微血管密度对前列腺癌预后潜力的比较。  |  Ekici, S., et al. 2004. Int J Cancer. 112: 121-9. PMID: 15305383
  4. 透明质酸酶基因 HYAL1 映射到人类染色体 3p21.2-p21.3 和小鼠染色体 9F1-F2,这是一个保守的候选肿瘤抑制基因座。  |  Csóka, AB., et al. 1998. Genomics. 48: 63-70. PMID: 9503017
  5. 透明质酸酶抑制剂对酸性和碱性透明质酸酶的不同选择性。  |  Isoyama, T., et al. 2006. Glycobiology. 16: 11-21. PMID: 16166602

订购信息

产品名称产品编号规格价格数量收藏夹

HYAL1 抗体 (1D10)

sc-101340
200 µg/ml
$316.00

HYAL1 (1D10): m-IgG Fc BP-HRP 套装

sc-527064
200 µg Ab; 10 µg BP
$354.00

HYAL1 (1D10): m-IgG1 BP-HRP 套装

sc-532437
200 µg Ab; 20 µg BP
$354.00

HYAL1 抗体 (1D10) AC

sc-101340 AC
500 µg/ml, 25% agarose
$416.00

HYAL1 抗体 (1D10) HRP

sc-101340 HRP
200 µg/ml
$316.00

HYAL1 抗体 (1D10) FITC

sc-101340 FITC
200 µg/ml
$330.00

HYAL1 抗体 (1D10) PE

sc-101340 PE
200 µg/ml
$343.00

HYAL1 抗体 (1D10) Alexa Fluor® 488

sc-101340 AF488
200 µg/ml
$357.00

HYAL1 抗体 (1D10) Alexa Fluor® 546

sc-101340 AF546
200 µg/ml
$357.00

HYAL1 抗体 (1D10) Alexa Fluor® 594

sc-101340 AF594
200 µg/ml
$357.00

HYAL1 抗体 (1D10) Alexa Fluor® 647

sc-101340 AF647
200 µg/ml
$357.00

HYAL1 抗体 (1D10) Alexa Fluor® 680

sc-101340 AF680
200 µg/ml
$357.00

HYAL1 抗体 (1D10) Alexa Fluor® 790

sc-101340 AF790
200 µg/ml
$357.00

Hi, are the fluorophore-conjugated antibodies usable for intracellular staining and flow cytometry?

Asked by: jonn
Anti-HYAL1 Antibody (1D10) is available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Answered by: Technical Service
Date published: 2024-05-07

Hi, I am concerning on the reactivity of this HYAL1 antibody with bovine hyaluronidases, especcially in bovine serum. Do you have information about that?

Asked by: kenny09
Thank you for your question. This antibody has not yet been tested in bovine samples and so that is not a recommended species at this time. We are still gathering data to show on our website. Check back for updates!
Answered by: Tech Service
Date published: 2019-12-06

What is the recommended secondary for this antibody?

Asked by: AbPolly
Thank you for your question. We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Service
Date published: 2017-02-02
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Rated 4 out of 5 by from Ottimo Funzionamento!Abbiamo acquistato questo anticorpo un mese fa e l'abbiamo testa su rene umano. Performa molto bene!
Date published: 2020-11-10
Rated 3 out of 5 by from Funktioniert in IHC für MausnierenWie im Bild funktioniert dieser AK in IHC für Mausnieren, allerdings haben wir Probleme, geeignete Zweit-AK zu finden, sodass wir bei weitem nicht so gute Ergebnisse wie im Musterbild haben. Wenn jemand Tipps hat, bitte posten.
Date published: 2018-02-02
Rated 5 out of 5 by from Absolut überzeugendes ErgebnisIch habe den Antikörper von Santa Cruz verwendet, weil ich sowohl mit einem Polyklonalen als auch mit einem Monoklonalen Hyal-1 Antikörper nicht zufrieden war. Bzw. keine überzeugenden Ergebnisse erzielen konnte. Anders mit diesem Antikörper. Der Westernblot ergab eine spezifische Bande, so wie man es sich wünscht. Ich bin sehr zufrieden.
Date published: 2017-02-28
Rated 5 out of 5 by from Worked in western blotWe used this antibody for a western blot and got a band at the correct molecular weight
Date published: 2017-01-03
Rated 5 out of 5 by from Publishable IHC data with human lungPublishable IHC data with human lung - SCBT Publication Review
Date published: 2015-02-22
Rated 5 out of 5 by from Produced great immunoperoxidase cytoplasmicProduced great immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human kidney tissue. -SCBT QC
Date published: 2015-02-18
Rated 5 out of 5 by from WB publishable data with human ASMCWB publishable data with human ASMC - SCBT Publication Review
Date published: 2014-12-17
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HYAL1 抗体 (1D10) is rated 4.6 out of 5 by 7.
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