Date published: 2025-10-26

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GSTP1 抗体 (3F2C2): sc-66000

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说明书
  • GSTP1 抗体 3F2C2 是小鼠单克隆 IgG1 κ,GSTP1抗体, 在20篇文献中引用,规格为200 µg/ml
  • 针对纯化的截短重组human的GSTP1
  • GSTP1 抗体 (3F2C2) 推荐用于WB, IP, IF 和 IHC(P),检测human 来源的 GSTP1
  • 抗GSTP1抗体(3F2C2)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是GSTP1 Antibody (3F2C2) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。这些试剂现与GSTP1 Antibody (3F2C2) 打包提供(请参阅下面的订购信息)。

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関連項目

GSTP1 抗体 (3F2C2) 是一种小鼠单克隆 IgG1 kappa 轻链抗体,可通过免疫印迹 (WB)、免疫沉淀 (IP)、免疫荧光 (IF) 和石蜡包埋切片免疫组织化学 (IHCP) 检测人类 GSTP1 蛋白。GSTP1 (3F2C2) 抗体有非共轭型和多种共轭型,包括琼脂糖、辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和多种 Alexa Fluor® 共轭物。GSTP1 蛋白又称谷胱甘肽 S-Transferase Pi 1,在解毒有害化合物(包括环境致癌物质和脂质氢过氧化物)方面发挥着至关重要的作用,从而保护细胞免受氧化应激。这种解毒过程对于维持细胞健康和防止可能导致癌症的损伤至关重要。GSTP1 蛋白在应对氧化应激时会上调,这凸显了 GSTP1 在细胞防御机制中的重要性。GSTP1 基因会发生 CpG 岛超甲基化,这种改变与前列腺癌的发生有关。在确诊为前列腺癌的男性尿液、射精和血浆等生物液体中可以检测到 GSTP1 基因的高甲基化,这表明 GSTP1 有可能成为早期癌症检测和筛查的重要生物标记物。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

GSTP1 抗体 (3F2C2) 参考文献:

  1. 位于 12q13-q14 的人类 Pi 类谷胱甘肽转移酶序列是一个反向转录的假基因。  |  Board, PG., et al. 1992. Genomics. 14: 470-3. PMID: 1427860
  2. 作为前列腺癌分子生物标记的 GSTP1 CpG 岛高甲基化。  |  Nakayama, M., et al. 2004. J Cell Biochem. 91: 540-52. PMID: 14755684
  3. 肿瘤坏死因子α处理的 K562 白血病细胞中 NF-kappaB 对谷胱甘肽 S 转移酶 P1-1 基因表达的调控。  |  Morceau, F., et al. 2004. Biochem Pharmacol. 67: 1227-38. PMID: 15013838
  4. 氧化应激诱导人红细胞白血病细胞株 K562 中 GSTP1 和 CYP3A4 的表达。  |  Nagai, F., et al. 2004. Biol Pharm Bull. 27: 492-5. PMID: 15056853
  5. 分析基因-基因相互作用的系统方法:微粒体环氧化物水解酶 EPHX 和谷胱甘肽 S-转移酶 GSTM1, GSTT1 和 GSTP1 基因位点的多态性与乳腺癌风险。  |  Spurdle, AB., et al. 2007. Cancer Epidemiol Biomarkers Prev. 16: 769-74. PMID: 17416769
  6. GSTP1高甲基化与肝细胞癌的临床意义和关联:荟萃分析。  |  Li, Y., et al. 2018. J Cancer Res Ther. 14: S486-S489. PMID: 29970711
  7. GSTP1作为辐射诱发肺损伤的新靶点。  |  Lei, X., et al. 2021. J Transl Med. 19: 297. PMID: 34238333
  8. SIRT5相关性赖氨酸脱甲基化对糖尿病心肌病心肌细胞热解质的抑制作用。  |  Wei, C., et al. 2024. Int J Biol Sci. 20: 585-605. PMID: 38169591
  9. 免疫组化法检测睾丸癌中的 P 糖蛋白和 GSTP1-1。  |  Katagiri, A., et al. 1993. Br J Cancer. 68: 125-9. PMID: 8100442
  10. 绘制大鼠谷胱甘肽转移酶(GST)基因图谱。  |  Klinga-Levan, K., et al. 1993. Hereditas. 119: 285-96. PMID: 8144363
  11. 用表达谷胱甘肽 S-转移酶的鼠伤寒沙门氏菌试验菌株研究致突变化合物的活化/解毒作用:卤代化合物, 芳香胺和黄曲霉毒素 B1 的研究。  |  Simula, TP., et al. 1993. Carcinogenesis. 14: 1371-6. PMID: 8330352
  12. 人类谷胱甘肽 S 转移酶 P1-1 基因:视黄酸和胰岛素对其表达的调节。  |  Xia, C., et al. 1993. Biochem J. 292 (Pt 3): 845-50. PMID: 8391258

订购信息

产品名称产品编号规格价格数量收藏夹

GSTP1 抗体 (3F2C2)

sc-66000
200 µg/ml
$316.00

GSTP1 (3F2C2): m-IgG Fc BP-HRP 套装

sc-528646
200 µg Ab; 10 µg BP
$354.00

GSTP1 (3F2C2): m-IgGκ BP-HRP 套装

sc-521083
200 µg Ab, 40 µg BP
$354.00

GSTP1 (3F2C2): m-IgG1 BP-HRP 套装

sc-543050
200 µg Ab; 20 µg BP
$354.00

GSTP1 抗体 (3F2C2) AC

sc-66000 AC
500 µg/ml, 25% agarose
$416.00

GSTP1 抗体 (3F2C2) HRP

sc-66000 HRP
200 µg/ml
$316.00

GSTP1 抗体 (3F2C2) FITC

sc-66000 FITC
200 µg/ml
$330.00

GSTP1 抗体 (3F2C2) PE

sc-66000 PE
200 µg/ml
$343.00

GSTP1 抗体 (3F2C2) Alexa Fluor® 488

sc-66000 AF488
200 µg/ml
$357.00

GSTP1 抗体 (3F2C2) Alexa Fluor® 546

sc-66000 AF546
200 µg/ml
$357.00

GSTP1 抗体 (3F2C2) Alexa Fluor® 594

sc-66000 AF594
200 µg/ml
$357.00

GSTP1 抗体 (3F2C2) Alexa Fluor® 647

sc-66000 AF647
200 µg/ml
$357.00

GSTP1 抗体 (3F2C2) Alexa Fluor® 680

sc-66000 AF680
200 µg/ml
$357.00

GSTP1 抗体 (3F2C2) Alexa Fluor® 790

sc-66000 AF790
200 µg/ml
$357.00

gstp1 in testis kanseriyle alakalı makale ya da çalışmalara nereden ulaşabilirim?

Asked by: egem98
Thank you for your question. All publications that cite use of this product are listed right here on its product page.
Answered by: Tech Support Europe
Date published: 2023-11-08

Quanto è il volume della vial di GSTP1 sc_66000?

Asked by: cidipi
Thank you for your question. Anti-GSTP1 Antibody (3F2C2): sc-66000 is provided as 200 µg in a volume of 1 ml PBS.
Answered by: Tech Support Europe
Date published: 2022-09-24

I have use GSTP1(3F2C2): sc-66000 for IHC-p of NSCLC tissue(1:50diluton).all case give 100%expression.one case is normal lung tissue. Why?

Asked by: Anumesh kumar Pathak
Thank you for your question. Please contact your local distributor for assistance in troubleshooting this antibody.
Answered by: Tech Service
Date published: 2019-09-11

What is the recommended secondary reagent to be used with this mouse monoclonal primary?

Asked by: jerojero
We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 14
Date published: 2017-02-04
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Rated 4 out of 5 by from Good IHC stainingI got very satisfactory IHC staining result with DAB in mouse liver.
Date published: 2019-11-22
Rated 5 out of 5 by from Clean blotThis antibody identifies hGSTP1 monomer by western blot without background.
Date published: 2017-11-29
Rated 5 out of 5 by from the result satisfiedGSTP1 Antibody  has manipulating conveniently with good control effect. When we used the antibody in our aim cell, the results show is very nice.
Date published: 2017-10-18
Rated 5 out of 5 by from It's really niceGSTP1 Antibody had powerful band detected in a large number of cell lines, improves the detecting sensitivity,the result satisfied.
Date published: 2017-10-09
Rated 5 out of 5 by from Potent and very specific antibodyA target protein of ~ 23 kDa was detected in human tissues (brain, testis, thymus, and muscle). No cross reactions were observed in 2 large g / ml, antibody concentration of target protein in the human tissue in the test.
Date published: 2017-05-19
Rated 5 out of 5 by from brilliantIt's lucky extremely that I succeeded to apply GSTP1 antibody. meanwhile, the bind I got yesterday is beautiful ,the background is so clear.
Date published: 2017-03-27
Rated 5 out of 5 by from IHCGood IHC staining in mouse pancreas tissue, the result is very satisfactory.
Date published: 2017-03-18
Rated 5 out of 5 by from good resultswe used the GSTP-1 for western blot ,the results are very clear.
Date published: 2017-03-08
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GSTP1 抗体 (3F2C2) is rated 4.9 out of 5 by 12.
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