Glycyrrhizin Acid Ammonium Salt CAS: 53956-04-0
MF: C42H62O16•NH3
MW: 839.97
A potent anti-viral agent.

Glycyrrhizin Acid Ammonium Salt (CAS 53956-04-0)

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同义词: Monoammonium glycyrrhizinate
应用; A potent anti-viral agent
CAS号码: 53956-04-0
纯度: ≥97%
分子量: 839.97
分子式: C42H62O16•NH3
* 参考分析证明 大量特定数据 (包括水 含量).
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Glycyrrhizin Ammonium salt is a constituent of the licorice root that has vital anti-viral activities that have been shown to inhibit the expression of 11β-HSD2 (11β-hydroxysteroid dehydrogenase type 2) via an indirect mechanism. Studies suggest that nitric oxide production is amplified in the macrophage cell line RAW264-7 and IFN-γ activated-macrophages. Furthermore, Glycyrrhizin stimulates the tumor cell killing effects of IFN -γ activated-macrophages. In addition the expression of COX-2 (cyclooxygenase-2) and NOS2 (inducible nitric oxide synthase, INOS) are inhibited by Glycyrrhizin. This product has been shown to suppress the growth and acid producing effects of S. mutans in vitro.


参考文献

1. Kondo, Y., et al. 1994. Biol. Pharm. Bull. 17: 759-761. PMID: 7920451
2. Tanahashi, T., et al. 2002. J. Steroid Biochem. Mol. Biol. 80: 441-447. PMID: 11983491
3. Cinatl, J., et al. 2003. Lancet. 361: 2045-2046. PMID: 12814717
4. Thirugnanam, S., et al. 2008. Oncol. Rep. 20: 1387-1392. PMID: 19020719
5. Tanaka, N., et al. 2009. J. Gastroenterol. 44: 577-582. PMID: 19352587

外观 :
Crystalline powder
物理状态 :
Solid
溶解度 :
Soluble in 1 M NH4OH (50 mg/ml), and Acetic Acid.
保存 :
Store at 4° C
熔点 :
209-211° C
折射率 :
n20D 1.62 (Predicted)
光学活性 :
α20/D 51.5°, c = 1.5 in ethanol
仅供科研使用。不可用于诊断或治疗。
德国水公害等级 :
2
RTECS :
LZ6500000
PubChem CID :
62074
默克索引 :
14: 4505
MDL 号码 :
MFCD00167400
EC号码 :
258-887-7
Beilstein 注册 :
3897076

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PMID: # 28670282  Fei, L. et al. 2017. Front Pharmacol. 8: 389.

PMID: # 2038692  Boutmy, E. et al. 1991. Soins. 55-56.

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