G_{γ 5} Antibody (3B8): sc-517161

Gγ 5 Antibody (3B8) is a mouse monoclonal IgG2a kappa light chain antibody that detects the G gamma 5 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-G gamma 5 antibody (3B8) is available as the non-conjugated format. G gamma 5 protein plays a crucial role in the function of heterotrimeric G proteins, which are essential for transmitting signals from cell surface receptors to various intracellular effectors. G proteins help relay information in response to extracellular stimuli, including hormones and neurotransmitters. G gamma 5 subunit interacts with specific G protein alpha and beta subunits, contributing to the formation of distinct G protein complexes that exhibit unique signaling properties. This specificity is vital for regulating diverse cellular responses, as different tissues express varying combinations of G protein subunits, leading to functional diversity in signaling pathways. Understanding G gamma 5 interactions and regulatory mechanisms is essential for elucidating its role in health and disease, making G gamma 5 (3B8) antibody a valuable tool for researchers studying G protein signaling dynamics.

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G_{γ 5} Antibody (3B8) References:

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7. Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human.  |  Blatt, C., et al. 1988. Proc Natl Acad Sci U S A. 85: 7642-6. PMID: 2902634