Date published: 2025-9-8

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Gemin2 抗体 (A-9): sc-166187

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说明书
  • Gemin2抗体(A-9)是小鼠单克隆IgG2b κ, 在2篇文献中引用,规格为200 µg/ml
  • 针对氨基酸2-101的抗原,在Gemin2的N-terminus处映射,human来源
  • 推荐用于 mouse, rat 和 human 来源的Gemin2 WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRP2b BP-HRP">m-IgG2b BP-HRPm-IgGκ BP-HRP是Gemin2 Antibody (A-9) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Gemin2 Antibody (A-9) 打包提供(请参阅下面的订购信息)。

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脊髓性肌萎缩症(SMA)是一种常染色体隐性遗传神经退行性疾病,其特点是脊髓中运动神经元的丧失。SMA是由运动神经元生存(SMN)基因中的缺失或功能丧失性突变引起的。Gemin2(前称SMN相互作用蛋白的SIP1)直接与SMN结合,并且是含有Gemin3(一种DEAD-box RNA解旋酶)、Gemin4、Gemin5和Gemin6以及几种剪接体snRNP蛋白质的SMN复合物的一部分。SMN复合物在细胞质中的剪接体snRNP组装中起着至关重要的作用,并且是细胞核中pre-mRNA剪接所必需的。它存在于细胞质和细胞核中,其核形态集中在被称为gems(卷曲体的Gemini)的亚核体中。SMN-Gemin2复合物与剪接体snRNAs U1和U5相关。Gemin2在脊髓中表达,可以通过TGFβ处理诱导,并且在几种E-钙粘蛋白阴性的人类癌细胞系中高表达。SMN在多种组织中表达,包括脑、肾、肝和脊髓,以及在骨骼肌和心肌中适度表达。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Gemin2 抗体 (A-9)

sc-166187
200 µg/ml
$316.00

Gemin2 (A-9): m-IgG Fc BP-HRP 套装

sc-537453
200 µg Ab; 10 µg BP
$354.00

Gemin2 (A-9): m-IgGκ BP-HRP 套装

sc-534725
200 µg Ab; 40 µg BP
$354.00

Gemin2 (A-9): m-IgG2b BP-HRP 套装

sc-549874
200 µg Ab; 10 µg BP
$354.00

What is the recommended fixation method for immunofluorescence staining with Gemin2 (A-9): sc-166187 monoclonal antibody?

Asked by: AbPolly
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from WB stains were greatWB stains were great!
Date published: 2015-09-04
Rated 5 out of 5 by from Produced beautiful immunofluorescence cytoplasmicProduced beautiful immunofluorescence cytoplasmic staining in formalin-fixed HepG2 cells. -SCBT QC
Date published: 2015-05-06
Rated 5 out of 5 by from Good Western Blot data of Gemin2 expressionGood Western Blot data of Gemin2 expression in HeLa and K-562 whole cell lysates. -SCBT QC
Date published: 2013-01-26
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Gemin2 抗体 (A-9) is rated 5.0 out of 5 by 3.
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