Date published: 2025-9-7
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G<sub>&beta;</sub>L Antibody (E-9) - Western Blotting - Image 372000
GβL 抗体 (E-9): sc-514982. A-375 (A), MCF7 (B), PC-3 (C), NIH/3T3 (D), M1 (E) 和 RPE-J (F) 全细胞裂解液中 GβL 表达的 Western 印迹分析.
GβL Antibody (E-9) - Western Blotting - Image 372000
GβL 抗体 (E-9): sc-514982. A-375 (A), MCF7 (B), PC-3 (C), NIH/3T3 (D), M1 (E) 和 RPE-J (F) 全细胞裂解液中 GβL 表达的 Western 印迹分析.
GβL Antibody (E-9) - Western Blotting - Image 333664
GβL (E-9): sc-514982. 在 A-375 (A) 和 HL-60 (B) 全细胞裂解液以及人类心脏 (C) 和人类大脑 (D) 组织提取物中 GβL 表达的 Western 印迹分析.
GβL Antibody (E-9) - Western Blotting - Image 371989
GβL 抗体 (E-9): sc-514982. M1 全细胞裂解液中 GβL 表达的 Western 印迹分析.
GβL 抗体 (E-9): sc-514982. A-375 (A), MCF7 (B), PC-3 (C), NIH/3T3 (D), M1 (E) 和 RPE-J (F) 全细胞裂解液中 GβL 表达的 Western 印迹分析.

GβL 抗体 (E-9): sc-514982

4.8(4)
寫評論提問

说明书
  • G beta L 抗体 E-9 是小鼠单克隆 IgG1 (kappa轻链)，GβL抗体，规格为200 µg/ml
  • 免疫原氨基酸序列71-326位于human物种的GβL的C-terminus
  • G beta L 抗体 (E-9) 推荐用于 WB, IP, IF 和 ELISA，检测mouse, rat 和human 来源的 GβL
  • 抗G beta L抗体（E-9）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取GβL (E-9): sc-514982的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP和 1 BP-HRP">m-IgG1 BP-HRP是GβL Antibody (E-9) for WB applications. 的首选辅助检测试剂，这些试剂现与GβL Antibody (E-9) 打包提供（请参阅下面的订购信息）。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

附加Heterotrimeric G Protein抗体，包括G α 11, G α 12, G α 13, G α i1, G α i2, G α i3, G α o, G α olf, G α q, G α q11, G α q14, G α q8, G α t, G α t1, G β和G β 1

GβL抗体（E-9）是一种小鼠单克隆IgG1κ轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）和酶联免疫吸附测定（ELISA）检测小鼠、大鼠和人类来源的GβL蛋白。GβL (E-9) 抗体有非结合型和多种结合型可供选择，包括琼脂糖、辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和多种 Alexa Fluor® 结合物。GβL蛋白，又称哺乳动物致死与SEC13蛋白8（mLST8），在调节mTOR信号通路中起着至关重要的作用，而mTOR信号通路对于细胞生长、增殖和存活至关重要。通过与mTOR和其他信号级联的相互作用，GβL有助于调节细胞对营养和生长因子的反应，因此GβL对于维持细胞稳态和影响代谢过程至关重要。GβL在其中发挥关键作用的mTOR通路失调与多种疾病有关，包括癌症和代谢紊乱，这凸显了研究GβL蛋白对于治疗干预的重要性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

GβL 抗体 (E-9) 参考文献:

  1. 胰岛素对脂肪细胞中一种新型 WD-40 重复蛋白的调控。  |  Rodgers, BD., et al. 2001. J Endocrinol. 168: 325-32. PMID: 11182770
  2. GbetaL是雷帕霉素敏感通路的正向调节器，它是雷帕霉素与mTOR之间营养敏感相互作用所必需的。  |  Kim, DH., et al. 2003. Mol Cell. 11: 895-904. PMID: 12718876
  3. raptor与mTOR分离是雷帕霉素诱导抑制mTOR功能的一种机制。  |  Oshiro, N., et al. 2004. Genes Cells. 9: 359-66. PMID: 15066126
  4. Rheb 与 mTOR 激酶结合并对其进行调节。  |  Long, X., et al. 2005. Curr Biol. 15: 702-13. PMID: 15854902
  5. 对营养敏感的猛禽-mTOR 途径和复合体的氧化还原调控。  |  Sarbassov, DD. and Sabatini, DM. 2005. J Biol Chem. 280: 39505-9. PMID: 16183647

订购信息

产品名称产品编号规格价格数量收藏夹

GβL 抗体 (E-9)

sc-514982
200 µg/ml
$316.00

GβL (E-9): m-IgG Fc BP-HRP 套装

sc-527965
200 µg Ab; 10 µg BP
$354.00

GβL (E-9): m-IgG1 BP-HRP 套装

sc-533338
200 µg Ab; 20 µg BP
$354.00

GβL 抗体 (E-9) AC

sc-514982 AC
500 µg/ml, 25% agarose
$416.00

GβL 抗体 (E-9) HRP

sc-514982 HRP
200 µg/ml
$316.00

GβL 抗体 (E-9) FITC

sc-514982 FITC
200 µg/ml
$330.00

GβL 抗体 (E-9) PE

sc-514982 PE
200 µg/ml
$343.00

GβL 抗体 (E-9) Alexa Fluor® 488

sc-514982 AF488
200 µg/ml
$357.00

GβL 抗体 (E-9) Alexa Fluor® 546

sc-514982 AF546
200 µg/ml
$357.00

GβL 抗体 (E-9) Alexa Fluor® 594

sc-514982 AF594
200 µg/ml
$357.00

GβL 抗体 (E-9) Alexa Fluor® 647

sc-514982 AF647
200 µg/ml
$357.00

GβL 抗体 (E-9) Alexa Fluor® 680

sc-514982 AF680
200 µg/ml
$357.00

GβL 抗体 (E-9) Alexa Fluor® 790

sc-514982 AF790
200 µg/ml
$357.00

what is GbetaL? is there a GenBank accession number?

Asked by: Lutz Birnbaumer
Thank you for your question. Protein GbetaL is also known as Target of rapamycin complex subunit LST8, or MLST8. GeneBank accession number is NP_001186102. This information is also available on our website under the &ldquo;Gene Info&rdquo; tab, below the ordering information and recommended support products.
Answered by: Technical Support
Date published: 2019-03-10

I need to use an antibody to detect the protein in samples of canine origin. Do you know if G&beta;L (E-9): sc-514982 mouse monoclonal antibody will work?

Asked by: Trav11
Thank you for your inquiry. Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity. We are available by phone, e-mail or chat.
Answered by: Technical Support
Date published: 2017-03-01
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Rated 5 out of 5 by from Good for Western BlotAntibody detects bands in human heart tissue extract and MCF7 whole cell lysate. Shown with Cruz Marker molecular weight standards, sc-2035. -SCBT QC
Date published: 2023-09-14
Rated 5 out of 5 by from Very good antibody !I used it for WB, dilution 1:1000, overnight incubation. I obtained a very good signal
Date published: 2019-11-21
Rated 5 out of 5 by from mLST8 (SCBT, #sc-514982, anti-Mouse)An extremely good antibody for WB. Picks up the target gene very well. No off-target binding. See the image attached. CELL LINE USED: HEK293 DILUTION USED: 1:1000; would recommend 1:2000 or 1:3000
Date published: 2017-08-06
Rated 4 out of 5 by from Good featureThe antibody was used in western blotting. Bands were clear.
Date published: 2017-01-16
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G β L 抗体 (E-9) is rated 4.8 out of 5 by 4.
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