Date published: 2025-9-7

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GAPDH 抗体 (6F7): sc-51907

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说明书
  • GAPDH 抗体 6F7 是小鼠单克隆 IgG1, 在61篇文献中引用,提供 100 µg/ml
  • 针对rabbit肌肉GADPH
  • 推荐用于 human 和 rabbit 来源的GAPDH WB, IP 和 ELISA检测; 也和以下物种反应,包括: canine
  • 看 GAPDH (0411): sc-47724,可查看有标记的 GAPDH 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成GAPDH 抗体 (6F7)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

GAPDH抗体(6F7)是一种针对兔肌糖醛酸-3-磷酸脱氢酶(GAPDH)的小鼠单克隆IgG1抗体,对人类和兔具有物种反应性。GAPDH是糖酵解过程中的关键酶,在有无机磷酸和烟酰胺腺嘌呤二核苷酸(NAD⁺)的情况下催化甘油醛-3-磷酸的可逆氧化磷酸化,这是碳水化合物代谢中能量产生的关键步骤。除了经典的代谢作用外,GAPDH还具有多种功能,包括作为尿嘧啶DNA糖基化酶参与DNA修复、参与转录激活、与RNA结合以及促进核RNA输出和DNA复制。GAPDH在肝癌、肺癌和前列腺癌等多种癌症中的表达显著上调,这使得GAPDH成为肿瘤学研究的重要标志物。在细胞凋亡过程中,GAPDH会转移到细胞核中,表明其参与了细胞凋亡的途径。此外,GAPDH还与与神经退行性疾病相关的神经元蛋白相互作用,包括β-淀粉样蛋白前体蛋白和亨廷顿蛋白,这凸显了GAPDH在神经生物学中的重要性。抗GAPDH抗体(6F7)为检测人类和家兔样本中的GAPDH提供了可靠的工具,推动了细胞代谢、疾病机理和治疗开发方面的研究。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

GAPDH 抗体 (6F7)

sc-51907
100 µg/ml
$316.00

does it reacts with mouse tissue ?

Asked by: sam22
Thank you for your question. sc-51907 is recommended for detection of GAPDH of human and rabbit origin by WB, IP and ELISA and is also reactive with additional species, including canine. We currently list some citations referring to this antibody on mouse samples.
Answered by: SCBT Heidelberg Support
Date published: 2018-11-27

Is this antibody available directly conjugated to HRP or fluorescent dyes?

Asked by: TinTin
Thank you for your question. All requests for directly conjugated versions of this antibody should be directed to our Special Orders team at specialorders@scbt.com Alternatively, consider using another excellent antibody for GAPDH, GAPDH (0411): sc-47724 as it is available conjugated to AC, HRP, FITC, PE, Alexa Fluor® 488 and Alexa Fluor® 647.
Answered by: Technical Service 11
Date published: 2017-02-03
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Rated 5 out of 5 by from Ideal western loading controlThis antibody serves as an ideal control for Western blots of human cell lines. We get a robust signal at the expected molecular weight using a dilution of 1:2000 in TBST + 3% BSA. This antibody is very clean as it detects only one band and gives no non-specific background.
Date published: 2020-04-12
Rated 3 out of 5 by from Did not cross react with budding yeast lysateNo band against total yeast cell lysate (S. cerevisiae) prepared by TCA ppt. However, I was able to detect bands with other GAPDH antibodies (sc-137179, sc-166545,and sc-365062)
Date published: 2018-02-12
Rated 4 out of 5 by from Works pretty wellGot the sample antibody. I used it to probe 12 different BOSC cell lysates lysed under different conditions. This was used as a loading control.
Date published: 2017-12-01
Rated 5 out of 5 by from work nicelyIr works well on vole's brain tissue extraction for western blot.
Date published: 2017-11-28
Rated 5 out of 5 by from Good specificityIt's easy to detect at dilution 1:500, It provides a strong band
Date published: 2017-04-28
Rated 5 out of 5 by from Good GAPDH antibodyGood, consistent signal for GAPDH detection. Great data obtained by Western blot.
Date published: 2017-02-07
Rated 4 out of 5 by from WB image was cleanWB image was clean, decent size band in HepG2. -SCBT QC
Date published: 2015-03-18
Rated 4 out of 5 by from Works well for WB in HeLa samplesWorks well for WB in HeLa samples. -SCBT QC
Date published: 2014-12-10
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GAPDH 抗体 (6F7) is rated 4.4 out of 5 by 8.
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