FOXP3 Antibody (6H3C5H3): sc-65988
- FOXP3 Antibody (6H3C5H3) is a mouse monoclonal IgG2b, cited in 2 publications, provided at 200 µg/ml
- raised against purified truncated recombinant FOXP3 of mouse origin
- recommended for detection of FOXP3 of mouse, rat and human origin by WB, IP and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- See FOXP3 (2A11G9): sc-53876 for FOXP3 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for FOXP3 Antibody (6H3C5H3). This work is in progress.
FOXP3 Antibody (6H3C5H3) is a mouse monoclonal IgG2b antibody that detects FOXP3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). FOXP3 is a critical transcription factor that plays a vital role in the regulation of immune responses, particularly in the development and function of regulatory T cells (Tregs). The proper functioning of FOXP3 is essential for maintaining immune tolerance and preventing autoimmune diseases, as mutations in the FOXP3 gene can lead to immune dysregulation disorders such as IPEX syndrome, which is characterized by severe autoimmune manifestations. FOXP3 contains a forkhead domain that enables binding to specific DNA sequences, thereby repressing the transcription of target genes involved in T cell activation. This regulatory mechanism is crucial for controlling the immune response and ensuring that T cells do not attack the body′s own tissues. Anti-FOXP3 antibody (6H3C5H3) is an invaluable tool for researchers studying immune regulation and the underlying mechanisms of autoimmune diseases, providing insights into the role of FOXP3 in both health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FOXP3 Antibody (6H3C5H3) | sc-65988 | 200 µg/ml | $322.00 | |||
FOXP3 Antibody (6H3C5H3) FITC | sc-65988 FITC | 200 µg/ml | $336.00 | |||
FOXP3 Antibody (6H3C5H3) PE | sc-65988 PE | 200 µg/ml | $349.00 |