Date published: 2025-9-6
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FOXM1 Antibody (A-11) - Western Blotting - Image 376739
FOXM1 抗体 (A-11): sc-271746. MCF7 (A) 和 SJRH30 (B) 全细胞裂解液中 FOXM1 表达的 Western 印迹分析.
FOXM1 抗体 (A-11): sc-271746. MCF7 (A) 和 SJRH30 (B) 全细胞裂解液中 FOXM1 表达的 Western 印迹分析.

FOXM1 抗体 (A-11): sc-271746

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说明书
  • FOXM1抗体(A-11)是小鼠单克隆IgG2a κ, 在37篇文献中引用，规格为200 µg/ml
  • 特异性抗原位于human物种的FOXM1的C-terminus的氨基酸737-763之间
  • 抗-FOXM1 抗体 (A-11) 推荐用于 WB, IP, IF 和 ELISA，检测mouse, rat 和human 来源的 all isoforms of FOXM1
  • 抗FOXM1抗体（A-11）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取FOXM1 (A-11): sc-271746的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前，我们还没有完成FOXM1 抗体 (A-11)的首选二抗检测试剂的鉴定。这项工作正在进行中。

快捷链接

相关产品
描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 FOX 抗体 包括 FOXC1, FOXC2, FOXD1, FOXD3, FOXE3, FOXF2, FOXJ1, FOXJ2, FOXK1和FOXL1

FOXM1抗体（A-11）是一种IgG2a κ小鼠单克隆FOXM1抗体（也被称为forkhead box FOXM1抗体），它可以通过WB、IP、IF和ELISA方法检测到小鼠、大鼠和人类来源的FOXM1的所有异构体。FOXM1抗体（A-11）有非偶联形式的抗FOXM1抗体，也有多种偶联形式的抗FOXM1抗体，包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。Fox转录因子家族是一大类共享一个被称为翼状螺旋或叉头域的常见DNA结合域的蛋白质。FOXM1，也被称为FKHL16、MPP2或Trident，主要在增殖细胞中表达。编码人类FOXM1的基因位于12p13染色体上。将FOXM1表达限制在增殖细胞中的转录元件位于起始密码子上游300bp处。FOXM1在胸腺、睾丸、小肠和结肠中的含量最为丰富。选择性剪接产生包含PEST区域的FOXM1A和FOXM1B异构体，这些区域与快速蛋白质降解有关。FOXM1表达的减少与细胞增殖的年龄相关缺陷有关。相反，在老年转基因小鼠的肝脏中增加FOXM1B表达可以恢复肝细胞DNA复制率，使其达到年轻肝脏中的较高水平。FOXM1B激活细胞周期蛋白B1、细胞周期蛋白D1和Cdc25B的转录。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

FOXM1 抗体 (A-11) 参考文献:

  1. 有丝分裂失调与人类衰老  |  Ly, DH., et al. 2000. Science. 287: 2486-92. PMID: 10741968
  2. 提高转基因小鼠肝细胞中叉头盒 M1B 转录因子的水平可防止再生肝脏出现与年龄相关的增殖缺陷。  |  Wang, X., et al. 2001. Proc Natl Acad Sci U S A. 98: 11468-73. PMID: 11572993
  3. 在小鼠肝脏再生过程中，叉头盒 m1b 转录因子对肝细胞 DNA 复制和有丝分裂至关重要。  |  Wang, X., et al. 2002. Proc Natl Acad Sci U S A. 99: 16881-6. PMID: 12482952
  4. 肝细胞核因子 3/ 叉头同源物 11 在胚胎和成人组织的增殖上皮细胞和间质细胞中表达。  |  Ye, H., et al. 1997. Mol Cell Biol. 17: 1626-41. PMID: 9032290
  5. 新型翼螺旋蛋白 WIN 的分子分析。表达模式, DNA 结合特性以及 DNA 结合域内的替代剪接。  |  Yao, KM., et al. 1997. J Biol Chem. 272: 19827-36. PMID: 9242644
  6. 人类 TRIDENT/HFH-11/FKHL16 基因：结构, 定位和启动子特征。  |  Korver, W., et al. 1997. Genomics. 46: 435-42. PMID: 9441747

订购信息

产品名称产品编号规格价格数量收藏夹

FOXM1 抗体 (A-11)

sc-271746
200 µg/ml
$316.00

FOXM1 抗体 (A-11) AC

sc-271746 AC
500 µg/ml, 25% agarose
$416.00

FOXM1 抗体 (A-11) HRP

sc-271746 HRP
200 µg/ml
$316.00

FOXM1 抗体 (A-11) FITC

sc-271746 FITC
200 µg/ml
$330.00

FOXM1 抗体 (A-11) PE

sc-271746 PE
200 µg/ml
$343.00

FOXM1 抗体 (A-11) Alexa Fluor® 488

sc-271746 AF488
200 µg/ml
$357.00

FOXM1 抗体 (A-11) Alexa Fluor® 546

sc-271746 AF546
200 µg/ml
$357.00

FOXM1 抗体 (A-11) Alexa Fluor® 594

sc-271746 AF594
200 µg/ml
$357.00

FOXM1 抗体 (A-11) Alexa Fluor® 647

sc-271746 AF647
200 µg/ml
$357.00

FOXM1 抗体 (A-11) Alexa Fluor® 680

sc-271746 AF680
200 µg/ml
$357.00

FOXM1 抗体 (A-11) Alexa Fluor® 790

sc-271746 AF790
200 µg/ml
$357.00

FOXM1 (A-11) 中和勝肽

sc-271746 P
100 µg/0.5 ml
$68.00

How should the blocking peptide sc-271746 P be used?

Asked by: jenniferc
Thank you for your question. The blocking peptide is intended to be used as a negative control by preadsorbing the FOXM1 (A-11): sc-271746 monoclonal antibody with it prior to application. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support 5
Date published: 2017-01-20
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Rated 5 out of 5 by from working goodI bought this 2 weeks ago and working very well in WB
Date published: 2021-06-12
Rated 4 out of 5 by from Good productIt is good antibodies in WB. It works in dilution 1:1000.
Date published: 2018-07-14
Rated 5 out of 5 by from Great antibody, good replacement for SC-500We struggled to find a replacement for the FOXM1 sc-500 antibody and this has proven to be a great replacement. Works great for WB (1:1000; secondary 1:5000; no non-specific bands; rat cells), IP, and IHC-P (1:75; rat tissue).
Date published: 2018-06-25
Rated 5 out of 5 by from work well for wb1:200 diluted for wb of rat protein,the band is quite strong
Date published: 2018-06-12
Rated 5 out of 5 by from Good and specific signal in western Blot analysisGood and specific signal in WB with HeLa and HEK293 cell extract. Antibody used at a dilution of 1:1000 in BSA O/N
Date published: 2018-04-12
Rated 4 out of 5 by from Good staining in IFStrong and specific staining in immunofluorescence at 1:1000 dilution of primary antibody.
Date published: 2018-02-16
Rated 5 out of 5 by from works wellWe tested the FOXM1 antibody and observed WB dilution of 1:200, indicating that the antibody band was clear.
Date published: 2017-10-26
Rated 5 out of 5 by from Best FOXM1 Antibody ever.I have tried all other FOXM1 antibody in the market and this one works very good for me.
Date published: 2017-06-21
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FOXM1抗体 (A-11) is rated 4.8 out of 5 by 13.
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