Date published: 2025-9-6
访问圣克鲁斯动物健康

021-6093-6350

SCBT Portrait Logo
Seach Input
联系我们
登陆账户
快速订购
购物车 (0)
FOXJ1 Antibody (3-19) - Western Blotting - Image 356805
FOXJ1 抗体 (3-19): sc-53139. H69AR (A), Hep G2 (B) 和 HeLa (C) 全细胞裂解液中 FOXJ1 表达的 Western 印迹分析.
FOXJ1 抗体 (3-19): sc-53139. H69AR (A), Hep G2 (B) 和 HeLa (C) 全细胞裂解液中 FOXJ1 表达的 Western 印迹分析.

FOXJ1 抗体 (3-19): sc-53139

4.5(11)
寫評論提問

说明书
  • FOXJ1 抗体 3-19 是小鼠单克隆 IgG1 κ，FOXJ1抗体, 在13篇文献中引用，规格为200 µg/ml
  • 免疫rat物种的重组FOXJ1
  • FOXJ1 抗体 (3-19) 推荐用于 WB, IP, IF 和 IHC(P)，检测mouse, rat 和human 来源的 FOXJ1
  • 抗FOXJ1抗体（3-19）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取FOXJ1 (3-19): sc-53139的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP 和 m-IgGκ BP-HRP 是 FOXJ1 抗体 (3-19) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与FOXJ1 抗体 (3-19) 组合成套装提供。 (请参阅下面的订购信息)。

快捷链接

相关产品
描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 FOX 抗体 包括 FOXC1, FOXC2, FOXD1, FOXD3, FOXE3, FOXF2, FOXJ1, FOXJ2, FOXK1和FOXL1

FOXJ1抗体（3-19）是一种小鼠单克隆IgG1 kappa轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）和免疫组织化学检测小鼠、大鼠和人源FOXJ1蛋白。FOXJ1抗体（3-19）有非结合型和多种结合型，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种Alexa Fluor®结合物。由421个氨基酸组成的叉头框J1（FOXJ1）蛋白作为转录因子发挥着关键作用，它通过抑制T细胞活性并抑制B细胞的体液免疫反应来调节免疫反应。FOXJ1通过抑制NFκB活性来防止自发性自身免疫，而NFκB活性通常与炎症过程有关。此外，FOXJ1对于纤毛的形成和左右轴的确定至关重要，因为FOXJ1可增强钙调蛋白的表达，而钙调蛋白是基底体锚定顶端细胞骨架所必需的蛋白质。FOXJ1的表达可作为上皮细胞分化、恢复和功能的早期标志物，而FOXJ1的异常表达与自身免疫性疾病和其他炎症有关。抗FOXJ1抗体（3-19）在免疫调节和细胞过程中具有多种应用和关键作用，是研究人员研究这些复杂生物途径的宝贵工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

FOXJ1 抗体 (3-19) 参考文献:

  1. 副黏液病毒感染对气道上皮细胞 Foxj1 表达, 纤毛生成和黏膜纤毛功能的影响  |  Look, DC., et al. 2001. Am J Pathol. 159: 2055-69. PMID: 11733356
  2. 气道上皮细胞中 ezrin 的顶端定位需要 Foxj1。  |  Huang, T., et al. 2003. J Cell Sci. 116: 4935-45. PMID: 14625387
  3. Foxj1 调节纤毛肺上皮细胞基底体与细胞骨架的锚定。  |  Gomperts, BN., et al. 2004. J Cell Sci. 117: 1329-37. PMID: 14996907
  4. Foxj1 在小鼠左右轴模式化过程中调控非对称基因表达。  |  Zhang, M., et al. 2004. Biochem Biophys Res Commun. 324: 1413-20. PMID: 15504371
  5. Foxj1 介导的 NF-kappa B 和 IL-6 的颉颃作用对 B 细胞活化的抑制。  |  Lin, L., et al. 2005. J Immunol. 175: 951-8. PMID: 16002694
  6. Foxj1 和 Inv 基因在小鼠内脏器官左右决定中的作用。  |  Tamakoshi, T., et al. 2006. Biochem Biophys Res Commun. 339: 932-8. PMID: 16325766
  7. 尖端技术：Foxj1 可防止自身免疫并抑制胸腺细胞排出。  |  Srivatsan, S. and Peng, SL. 2005. J Immunol. 175: 7805-9. PMID: 16339515
  8. 热带爪蟾中 FoxJ1.2, FoxJ2 和 FoxQ1 的发育表达。  |  Choi, VM., et al. 2006. Gene Expr Patterns. 6: 443-7. PMID: 16461016
  9. 鉴定 FOXJ1 的单核苷酸多态性及其与过敏性鼻炎的关系。  |  Li, CS., et al. 2006. J Hum Genet. 51: 292-297. PMID: 16518568
  10. FOXJ1的敲除抑制喉鳞状细胞癌细胞的增殖、迁移、侵袭和糖酵解。  |  Liu, L., et al. 2019. J Cell Biochem. 120: 15874-15882. PMID: 31062413
  11. 杂合FOXJ1突变导致不完全的脑膜细胞分化并导致沟通性脑积水。  |  Hou, CC., et al. 2023. Cell Mol Neurobiol. 43: 4103-4116. PMID: 37620636
  12. 叉头转录因子Foxj1控制脊椎动物嗅觉纤毛的生物发生和感觉神经元的分化。  |  Rayamajhi, D., et al. 2024. PLoS Biol. 22: e3002468. PMID: 38271330

订购信息

产品名称产品编号规格价格数量收藏夹

FOXJ1 抗体 (3-19)

sc-53139
200 µg/ml
$316.00

FOXJ1 (3-19): m-IgG Fc BP-HRP 套装

sc-528553
200 µg Ab; 10 µg BP
$354.00

FOXJ1 (3-19): m-IgGκ BP-HRP 套装

sc-520952
200 µg Ab, 40 µg BP
$354.00

FOXJ1 (3-19): m-IgG1 BP-HRP 套装

sc-542990
200 µg Ab; 20 µg BP
$354.00

FOXJ1 抗体 (3-19) AC

sc-53139 AC
500 µg/ml, 25% agarose
$416.00

FOXJ1 抗体 (3-19) HRP

sc-53139 HRP
200 µg/ml
$316.00

FOXJ1 抗体 (3-19) FITC

sc-53139 FITC
200 µg/ml
$330.00

FOXJ1 抗体 (3-19) PE

sc-53139 PE
200 µg/ml
$343.00

FOXJ1 抗体 (3-19) Alexa Fluor® 488

sc-53139 AF488
200 µg/ml
$357.00

FOXJ1 抗体 (3-19) Alexa Fluor® 546

sc-53139 AF546
200 µg/ml
$357.00

FOXJ1 抗体 (3-19) Alexa Fluor® 594

sc-53139 AF594
200 µg/ml
$357.00

FOXJ1 抗体 (3-19) Alexa Fluor® 647

sc-53139 AF647
200 µg/ml
$357.00

FOXJ1 抗体 (3-19) Alexa Fluor® 680

sc-53139 AF680
200 µg/ml
$357.00

FOXJ1 抗体 (3-19) Alexa Fluor® 790

sc-53139 AF790
200 µg/ml
$357.00

Please provide the Japan SDS for sc-53139 AF594 Or, could you please provide a statement in writing (e.g. by email) to the effect that the product is not subject to the legislations: 毒劇法、消防法、化審法、労働安全衛生法（第55条、56条、57条、57条のの２）、PRTR法、カルタヘナ法

Asked by: SHspac
Thank you for your question. Santa Cruz Biotechnology antibodies are non-hazardous products for which no MSDS, SDS or COA is required.Please contact our Technical Service Department if you have any other questions. Our Asian Technical Service team is available at (+86) 021-60936350 or asia@scbio.cn or by live chat on our website.
Answered by: Sen Li
Date published: 2025-02-05

If I want to use this antibody for a double stain, how can I do so with only mouse monoclonal antibodies?

Asked by: Cweed
We recommend using a directly conjugated primary antibody. This product, sc-53139, is available conjugated to AF488, AF647, or FITC.
Answered by: Technical Support 4
Date published: 2017-01-17
  • y_2025, m_8, d_27, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_53139, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 105ms
  • QUESTIONS, PRODUCT
Rated 1 out of 5 by from Immunfluorescence murine airway organoidsDid not work for IF-C, using murine epithelial airway organoids, fixed in 4% PFA, permeabilization solution: 0.5% Triton in PBS, blocking solution: 1x ROTI Block, Dilution: 1:50.
Date published: 2025-04-17
Rated 5 out of 5 by from Reseña generalYo compre un producto y esta muy bueno ya que me lo entregaron al momento
Date published: 2023-08-27
Rated 1 out of 5 by from Immunohistochemistry frozen & free floatingI tested the antibody for an immunohistochemistry on mouse embryo E12.5, fixed 1h in paraformaldehyde 4%. Dilution: 1/50, Permeabilization solution: PBS 1X- Triton 0,2%(& 0,4%) - Goat serum 10%. It did not work.
Date published: 2017-10-27
Rated 3 out of 5 by from 功能未知是空管，空管空管空管空管空管空管空管空管空管空管空管空管空管空管空管空管空管空管空管空管，所以无从评价
Date published: 2017-08-15
Rated 5 out of 5 by from Great for Western blotFOXJ1 (3-19) gives a strong band at 58 kDa in Hep G2 and HeLa whole cell lysates for Western blotting (WB).
Date published: 2017-01-23
Rated 5 out of 5 by from Outstanding western dataVery clear western data; strong signal with low background
Date published: 2017-01-23
Rated 5 out of 5 by from work well in WBI bought this antibody four month ago，tesed with human cell，and obtained good datas，the antibody is very good
Date published: 2016-12-27
Rated 5 out of 5 by from Published data for IHC in human HAEC cell linePublished data for IHC in human HAEC cell line. -SCBT Publication Review
Date published: 2015-04-21
  • y_2025, m_8, d_26, h_8
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_12
  • loc_zh_CN, sid_53139, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 9ms
  • REVIEWS, PRODUCT
FOXJ1 抗体 (3-19) is rated 4.2 out of 5 by 12.
  • y_2025, m_8, d_26, h_8
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_12
  • loc_zh_CN, sid_53139, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 85ms
  • REVIEWS, PRODUCT
021-6093-6350
访问 Santa Cruz Animal Health|访问 San Juan Ranch
Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打0086-021-60936350联系我们。
版权所有© 2007-2025 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。