FANCF Antibody (G-4): sc-271397
- FANCF Antibody (G-4) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 41-350 of FANCF of human origin
- recommended for detection of FANCF of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for FANCF Antibody (G-4) for WB applications. These reagents are now offered in bundles with FANCF Antibody (G-4) (see ordering information below).
FANCF Antibody (G-4) is a mouse monoclonal IgG2b antibody that detects FANCF in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FANCF plays a crucial role in the Fanconi anemia (FA) pathway, which is essential for maintaining genomic stability and responding to DNA damage. FANCF (G-4) antibody enables detection of a protein required for FANCD2 activation, a key component in the FA pathway, and helps stabilize other FA complex subunits. Mutations in FANCF can lead to impaired DNA repair mechanisms, resulting in chromosomal instability and increased cancer susceptibility. The human FANCF gene is located on chromosome 11p15 and encodes a nuclear protein sharing homology with prokaryotic RNA-binding protein ROM, highlighting evolutionary significance. Anti-FANCF antibody (G-4) provides researchers valuable insights into molecular mechanisms underlying Fanconi anemia and associated pathologies, supporting studies in cancer research and genetic disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FANCF Antibody (G-4) | sc-271397 | 200 µg/ml | $322.00 | |||
FANCF Antibody (G-4): m-IgGκ BP-HRP Bundle | sc-534947 | 200 µg Ab; 40 µg BP | $361.00 | |||
FANCF Antibody (G-4): m-IgG2b BP-HRP Bundle | sc-549319 | 200 µg Ab; 10 µg BP | $361.00 |