Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US, Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxesShips via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal health products, bulky and/or heavy items
FAM65B Antibody (3J7) is a high quality monoclonal FAM65B antibody (also designated FAM65B antibody) suitable for the detection of the FAM65B protein of human origin. FAM65B Antibody (3J7) is available as the non-conjugated anti-FAM65B antibody. FAM65B, also known as C6orf32, DIFF28 or PL48, is a 1,068 amino acid protein that belongs to the FAM65 family. FAM65B exists as two alternatively spliced isoforms; isoform 1 is found in brain while isoform 2 is expressed in fetal primary myoblasts during differentiation. Isoform 2 may be important for cellular differentiation, filopodia formation and cytoskeletal rearrangement. Cells missing isoform 2 have a large reduction of myotube formation, yet overexpression induces filopodial formation. The gene encoding FAM65B maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson′s disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
种属 | 基因名称 | 基因ID | 染色质位置 | 亚型(mRNA)即位号码 | 蛋白质即位号码 | OMIM™ 号码 |
---|---|---|---|---|---|---|
Human | FAM65B | 9750 | 6p22.3 | XM_006715275, XM_006715277, XM_006715279, XM_006715281, XM_011515007, XM_011515008, XM_011515009, XM_011515010, XM_011515012, XM_017011523, XM_017011524, XM_017011525, XM_017011526, XM_017011527, NM_001286445, NM_001286446, NM_001286447, NM_001346031, NM_001346032, NM_014722, NM_015864 | Q9Y4F9 | n/a |