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ephrin-A3 抗体 (D-8): sc-393727

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说明书
  • ephrin-A3 抗体 D-8 是小鼠单克隆 IgG3 (kappa轻链),ephrin-A3抗体,规格为200 µg/ml
  • 特异性抗原位于human物种的ephrin-A3的C-terminus的氨基酸177-205之间
  • 推荐用于 mouse, rat 和 human 来源的ephrin-A3 WB, IP, IF 和 ELISA检测; 也和以下物种反应,包括: 和 equine, canine and bovine
  • 关于如何获取ephrin-A3 (D-8): sc-393727免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG3 BP-HRP是ephrin-A3 Antibody (D-8) 适用于 WB 应用。 的首选辅助检测试剂,该试剂现与ephrin-A3 Antibody (D-8) 搭配使用(请参阅下面的订购信息)。

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ephrin-A3抗体(D-8)是一种IgG3 κ小鼠单克隆ephrin-A3抗体(也称为Ephrin A3抗体或EFNA3抗体),可通过WB、IP、IF和ELISA检测小鼠、大鼠和人源的ephrin-A3蛋白。ephrin-A3抗体(D-8)可以以非偶联抗ephrin-A3抗体的形式提供。Eph亚家族受体代表了迄今为止鉴定的最大的受体蛋白激酶组。有越来越多的证据表明,它们参与中枢神经系统功能及其发育。Eph受体的配体包括ephrin-A1(LERK-1/B61),被鉴定为EphA2(Eck)受体的配体;ephrin-A2(ELF-1),被鉴定为EphA3和EphA4(Sek)受体的配体;ephrin-A3(LERK-3),被鉴定为EphA5(Ehk1)和EphA3(Hek)受体的配体;ephrin-A4(LERK-4),被鉴定为EphA3受体的配体;ephrin-A5(AL-1),被鉴定为EphA5(REK7)的配体;ephrin-B1(LERK-2),被鉴定为EphB1(Elk)和EphB2(Cek5)受体的配体;ephrin-B2(LERK-5),被鉴定为EphB1、EphB3(Cek10)和EphB2受体的配体;以及ephrin-B3(LERK-8),被鉴定为EphB1的配体。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

ephrin-A3 抗体 (D-8) 参考文献:

  1. Ephrin-A3反向信号调节瞬时性整体缺血后的海马神经元损伤和星形胶质细胞谷氨酸转运。  |  Yang, J., et al. 2014. J Neurochem. 131: 383-94. PMID: 25040798
  2. ephrin-A3和ephrin-A4有助于小胶质细胞诱导的脑内皮细胞血管生成。  |  Li, Y., et al. 2014. Anat Rec (Hoboken). 297: 1908-18. PMID: 25070915
  3. 小鼠听觉脑干的声调图谱精度和听觉功能需要Ephrin-A3。  |  Hoshino, N., et al. 2021. J Comp Neurol. 529: 3633-3654. PMID: 34235739
  4. Ephrin-A3/EphA2轴调节细胞代谢可塑性,增强缺氧性肝细胞癌的癌症干性。  |  Husain, A., et al. 2022. J Hepatol. 77: 383-396. PMID: 35227773
  5. 膀胱尿路上皮癌中 Ephrin A3 的临床病理和预后意义。  |  Wang, YF., et al. 2023. Oncol Lett. 26: 524. PMID: 37927410
  6. ELF-1的鉴定和克隆,ELF-1是Mek4和Sek受体酪氨酸激酶的发育表达配体。  |  Cheng, HJ. and Flanagan, JG. 1994. Cell. 79: 157-68. PMID: 7522971
  7. ELF-2是Eph配体家族的一个新成员,在小鼠胚胎后脑和新形成的体节区域节段性表达。  |  Bergemann, AD., et al. 1995. Mol Cell Biol. 15: 4921-9. PMID: 7651410
  8. 克隆参与轴突束形成的 Eph 相关酪氨酸激酶受体配体 AL-1。  |  Winslow, JW., et al. 1995. Neuron. 14: 973-81. PMID: 7748564
  9. 受体酪氨酸激酶 hek 和 elk 的配体:分离编码蛋白质家族的 cDNA。  |  Kozlosky, CJ., et al. 1995. Oncogene. 10: 299-306. PMID: 7838529
  10. eph相关酪氨酸激酶受体配体家族的分子特征。  |  Beckmann, MP., et al. 1994. EMBO J. 13: 3757-62. PMID: 8070404
  11. B61 是 ECK 受体蛋白酪氨酸激酶的配体。  |  Bartley, TD., et al. 1994. Nature. 368: 558-60. PMID: 8139691
  12. Elk-L3是Eph家族受体酪氨酸激酶的一种新型跨膜配体,在胚胎底板, 顶板和后脑节段中表达。  |  Gale, NW., et al. 1996. Oncogene. 13: 1343-52. PMID: 8808709

订购信息

产品名称产品编号规格价格数量收藏夹

ephrin-A3 抗体 (D-8)

sc-393727
200 µg/ml
$316.00

ephrin-A3 (D-8): m-IgG3 BP-HRP 套装

sc-550598
200 µg Ab; 40 µg BP
$354.00

ephrin-A3 (D-8) 中和勝肽

sc-393727 P
100 µg/0.5 ml
$68.00

May I know why the protein band is shown above 43kDa for the image posted? The molecular weight of the EphrinA3 is 32-38 kDa.

Asked by: jeryhery
Thank you for your question. It would be helpful if you could call us, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Support
Date published: 2021-07-22

What application is the blocking peptide sc-393727 P appropriate for?

Asked by: Trav11
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-25
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Rated 5 out of 5 by from Satisfactory Western blot data of ephrinSatisfactory Western blot data of ephrin-A3 expression in non-transfected 293T, human ephrin-A3 transfected 293T Hep G2, Jurkat and A549 whole cell lysates. -SCBT QC
Date published: 2014-08-19
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ephrin-A3 抗体 (D-8) is rated 5.0 out of 5 by 1.
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