Echinococcus granulosus Antibody (EHG): sc-51875

Echinococcus granulosus Antibody (EHG) is a mouse monoclonal IgG1 antibody that detects Echinococcus granulosus protein by western blotting (WB). Anti-Echinococcus granulosus antibody (EHG) is available as a non-conjugated format. Echinococcus granulosus, commonly known as the Hydatid worm, is a cyclophyllid cestode that primarily resides in the small intestine of canids during adult stage. This parasite causes Hydatid disease in intermediate hosts, including livestock and humans, making Echinococcus granulosus a significant public health concern. Adult tapeworms measure approximately 5 mm in length and feature three proglottids when intact, along with four suckers on the scolex and a rostellum equipped with hooks. Echinococcus granulosus eggs are excreted in infected canid feces and can transmit to humans through contact with contaminated environments or animals. Once ingested, embryos hatch, penetrate intestinal mucosa, and enter portal circulation, where cysts form in various organs, particularly the liver and lungs. Understanding Echinococcus granulosus structure is crucial, as unique anatomical features, such as the rostellum and hooks, play a vital role in attachment to intestinal walls of definitive hosts, facilitating nutrient absorption and survival. Anti-Echinococcus granulosus antibody (EHG) serves as an essential tool for studying parasite biology and health impacts.

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Echinococcus granulosus Antibody (EHG) References:

1. Association of some HLA-DRB1 antigens with Echinococcus granulosus specific humoral immune response.  |  Azab, ME., et al. 2004. J Egypt Soc Parasitol. 34: 183-96. PMID: 15125526
2. Purification, cloning, and expression of the mitochondrial malate dehydrogenase (mMDH) from protoscolices of Echinococcus granulosus.  |  Agüero, F., et al. 2004. Mol Biochem Parasitol. 137: 207-14. PMID: 15383291
3. Cellular organization and appearance of differentiated structures in developing stages of the parasitic platyhelminth Echinococcus granulosus.  |  Martínez, C., et al. 2005. J Cell Biochem. 94: 327-35. PMID: 15526286
4. Comparative analysis of the diagnostic performance of six major Echinococcus granulosus antigens assessed in a double-blind, randomized multicenter study.  |  Lorenzo, C., et al. 2005. J Clin Microbiol. 43: 2764-70. PMID: 15956395
5. Preliminary study of the presence of antibodies against excretory-secretory antigens from protoscoleces of Echinococcus granulosus in dogs with intestinal echinococcosis.  |  Carmena, D., et al. 2005. Mem Inst Oswaldo Cruz. 100: 311-7. PMID: 16113875
6. Identification of membrane-bound and secreted proteins from Echinococcus granulosus by signal sequence trap.  |  Rosenzvit, MC., et al. 2006. Int J Parasitol. 36: 123-30. PMID: 16229848
7. High polymorphism in genes encoding antigen B from human infecting strains of Echinococcus granulosus.  |  Kamenetzky, L., et al. 2005. Parasitology. 131: 805-15. PMID: 16336734
8. In vitro effects of flubendazole on Echinococcus granulosus protoscoleces.  |  Elissondo, M., et al. 2006. Parasitol Res. 98: 317-23. PMID: 16374619
9. Shared and non-shared antigens from three different extracts of the metacestode of Echinococcus granulosus.  |  Carmena, D., et al. 2005. Mem Inst Oswaldo Cruz. 100: 861-7. PMID: 16444417