Date published: 2025-9-6

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E-cadherin 抗体 (1.B.54): sc-71009

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说明书
  • E-cadherin抗体(1.B.54)是小鼠单克隆IgG1 κ, 在67篇文献中引用,规格为200 µg/ml
  • 针对human乳腺癌细胞系T471
  • 推荐用于 human 来源的E-cadherin WB, IP, IF 和 FCM检测
  • 看 E-cadherin (G-10): sc-8426,可查看有标记的 E-cadherin 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是E-cadherin Antibody (1.B.54) for WB applications. 的首选辅助检测试剂,这些试剂现与E-cadherin Antibody (1.B.54) 打包提供(请参阅下面的订购信息)。

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E-cadherin抗体(1.B.54)是一种小鼠单克隆IgG1抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和流式细胞术(FCM)等方法检测人体样本中的E-cadherin。E-cadherin通过介导细胞间粘附来维持上皮组织的完整性,这对于维持正常的组织结构和功能至关重要。E-钙黏蛋白主要位于细胞膜上,与邻近细胞形成粘附连接,从而有助于形成紧密的细胞层,这对于皮肤和胃肠道内壁等组织的屏障功能至关重要。E-钙黏蛋白的位置至关重要,因为功能障碍或缺失通常与细胞运动和侵袭性增强有关,而这是癌症进展的标志。E-cadherin的细胞外结构域与其他钙粘蛋白和细胞质蛋白(包括β-catenin)相互作用,促进调节细胞增殖和分化的信号通路。抗E-cadherin抗体(1.B.54)是研究人员研究细胞粘附机制、上皮完整性以及E-cadherin在各种疾病中的意义的宝贵工具,特别是在癌症研究中,其表达水平可作为预后指标。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

E-cadherin 抗体 (1.B.54)

sc-71009
200 µg/ml
$316.00

E-cadherin (1.B.54): m-IgG Fc BP-HRP 套装

sc-539329
200 µg Ab; 10 µg BP
$354.00

E-cadherin (1.B.54): m-IgG1 BP-HRP 套装

sc-541413
200 µg Ab; 20 µg BP
$354.00

Will this anibody work on cynomolgus monkey cells?

Asked by: Cpass
Thank you for your question. This antibody has not yet been tested in monkey and so that is not a recommended species at this time. We are still gathering data to show on our website. Check back for updates!
Answered by: Tech Service
Date published: 2020-02-18

What blocking solution should I use with E-cadherin (1.B.54): sc-71009 monoclonal antibody for Western blot?

Asked by: DefinitelyNotMatt
Thank you for your question. We recommend blocking with Blotto (either TBS Blotto A: sc-2333 or TBS Blotto B: sc-2335). Our Western blot protocol can be found here: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-04-13
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Rated 4 out of 5 by from Nice clean Bands in westernNice clean bands in western blot with a 1:500 dilution over night
Date published: 2017-11-28
Rated 5 out of 5 by from Great antibody for westerns, human specificThis antibody works great for western blots, especially together with the Kappa-binding-HRP as secondary. Also, this antibody seems to be specific for human E-cadherin.
Date published: 2017-02-14
Rated 5 out of 5 by from Good antibodyI love it.It works well and no matter IHC-P or IHC-F ,both of them can get good results.I repeated for several times and it was stable.
Date published: 2017-02-13
Rated 5 out of 5 by from Great, versatile antibodyThe E-cadherin Antibody (1.B.54): sc-71009 works well for a variety of applications including WB, IP, IF and FCM. This antibody has also been cited multiple times for further verification.
Date published: 2017-01-17
Rated 5 out of 5 by from Works great for WB of human oral cancer cell linesWorks great for WB of human oral cancer cell lines, SCC-25 cells, OECM-1 cells
Date published: 2015-12-21
Rated 4 out of 5 by from Works great for WB of human RT4Works great for WB of human RT4, HT1376, and T24 cell lines
Date published: 2015-12-16
Rated 5 out of 5 by from Good in WB with human primary fibroblastsGood in WB with human primary fibroblasts
Date published: 2014-11-25
Rated 5 out of 5 by from Works well with human tumor cells in WBWorks well with human tumor cells in WB -SCBT Publication Review
Date published: 2014-07-07
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E-cadherin抗体 (1.B.54) is rated 4.8 out of 5 by 9.
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