Date published: 2025-9-7

021-6093-6350

SCBT Portrait Logo
Seach Input

DUSP8 抗体 (B-9): sc-271250

4.5(4)
寫評論提問

说明书
  • DUSP8 抗体 B-9 是小鼠单克隆 IgG3 κ,DUSP8抗体, 在2篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的DUSP8的N-terminus附近的氨基酸18-43之间
  • 推荐用于 human 来源的DUSP8 WB, IP, IF, IHC(P) 和 ELISA检测
  • 关于如何获取DUSP8 (B-9): sc-271250免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG3 BP-HRP 是DUSP8 抗体 (B-9) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与DUSP8 抗体 (B-9) 组合成套装提供。 (请参阅下面的订购信息)。

快捷链接

関連項目

DUSP8抗体(B-9)是一种IgG3 κ小鼠单克隆DUSP8抗体(也称为VH5抗体),可通过蛋白质印迹、免疫沉淀、免疫荧光、免疫组织化学(石蜡)和酶联免疫吸附试验检测人类来源的DUSP8蛋白。DUSP8抗体(B-9)为非偶联抗DUSP8抗体。丝裂原活化蛋白(MAP)激酶是一大类参与信号转导通路的蛋白质,这些通路可被一系列刺激物激活,并介导细胞内的多种生理和病理变化。双特异性磷酸酶(DSPs)是蛋白质酪氨酸磷酸酶(PTP)基因超家族的一个亚类,它们选择性地去磷酸化MAP激酶内的关键磷酸苏氨酸和磷酸酪氨酸残基。DSP基因表达由许多生长因子和/或细胞应激诱导,从而负调控MAP激酶超家族成员,包括MAPK/ERK、SAPK/JNK和p38。DUSP8使SAPK/JNK和p38失活,主要在成人大脑、心脏和骨骼肌中表达。它定位于细胞质中,受神经生长因子和胰岛素诱导。DUSP8可能在导致酒精依赖发展的病理生理机制中发挥作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

DUSP8 抗体 (B-9) 参考文献:

  1. 双特异性磷酸酶:控制 MAP 激酶功能的基因家族。  |  Camps, M., et al. 2000. FASEB J. 14: 6-16. PMID: 10627275
  2. 研究酒精依赖症中的 DUSP8 和 CALCA。  |  Hink, RL., et al. 2003. Addict Biol. 8: 305-12. PMID: 13129832
  3. hVH-5:一种在大脑中含量丰富的蛋白酪氨酸磷酸酶,可使丝裂原活化蛋白激酶失活。  |  Martell, KJ., et al. 1995. J Neurochem. 65: 1823-33. PMID: 7561881
  4. 新出现的双特异性 MAP 激酶磷酸化酶家族。  |  Keyse, SM. 1995. Biochim Biophys Acta. 1265: 152-60. PMID: 7696343
  5. 双特异性磷酸酶的功能研究。  |  Sun, H. 1998. Methods Mol Biol. 84: 307-18. PMID: 9666459

订购信息

产品名称产品编号规格价格数量收藏夹

DUSP8 抗体 (B-9)

sc-271250
200 µg/ml
$316.00

DUSP8 (B-9): m-IgG3 BP-HRP 套装

sc-550560
200 µg Ab; 40 µg BP
$354.00

DUSP8 (B-9) 中和勝肽

sc-271250 P
100 µg/0.5 ml
$68.00

Has this product ever been tested for use in mouse?

Asked by: Richard123
Thank you for your question. DUSP8 Antibody (B-9): sc-271250 is only recommended for detection of DUSP8 of human origin by WB, IP, IF, IHC(P) and ELISA. There is no data indicating that this antibody also works in murine tissues.
Answered by: Tech Support Europe
Date published: 2019-06-04

What application is the blocking peptide sc-271250 P appropriate for?

Asked by: jenniferc
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_8, d_28, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_271250, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 105ms
  • QUESTIONS, PRODUCT
Rated 3 out of 5 by from No band using airway smooth muscle cellsWestern had no visible band from 15ug total protein using human airway smooth muscle cell lysates (1:100).
Date published: 2017-07-31
Rated 5 out of 5 by from Great monoclonal antibodyRobust staining with paraffin-embedded human brain tissue and specific band produced with SK-N-SH whole cell lysate.
Date published: 2017-02-08
Rated 5 out of 5 by from Excellent immunoperoxidase cytoplasmic stainingExcellent immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human brain tissue. -SCBT QC
Date published: 2015-05-21
Rated 5 out of 5 by from Nice Western Blot data of DUSP8 expression in SKNice Western Blot data of DUSP8 expression in SK-N-SH whole cell lysate. -SCBT QC
Date published: 2014-06-28
  • y_2025, m_8, d_28, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_271250, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 7ms
  • REVIEWS, PRODUCT
DUSP8 抗体 (B-9) is rated 4.5 out of 5 by 4.
  • y_2025, m_8, d_28, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_271250, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 104ms
  • REVIEWS, PRODUCT