Date published: 2025-9-9

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DUOX1 抗体 (H-9): sc-393096

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说明书
  • DUOX1 抗体 H-9 是小鼠单克隆 IgG1 κ,DUOX1抗体, 在6篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列611-675位于human物种的DUOX1的内部区域内
  • DUOX1 抗体 (H-9) 推荐用于 WB, IP, IF 和 ELISA,检测human 和mink 来源的 DUOX1
  • 抗DUOX1抗体(H-9)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取DUOX1 (H-9): sc-393096免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是DUOX1 Antibody (H-9) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与DUOX1 Antibody (H-9) 打包提供(请参阅下面的订购信息)。

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関連項目

DUOX1抗体(H-9)是一种IgG1 κ小鼠单克隆DUOX1抗体(也称为THOX1抗体或LNOX1抗体),可通过WB、IP、IF和ELISA检测人类、水貂来源的DUOX1蛋白。DUOX1抗体(H-9)既有非偶联形式的抗DUOX1抗体,也有多种偶联形式的抗DUOX1抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。双氧化酶1(DUOX1)是糖蛋白p91Phox的同源物,在气道上皮细胞中表达并产生活性氧(ROS)。DUOX1,也被称为NADPH甲状腺氧化酶或大NOX1,是一种多通道膜蛋白,主要在甲状腺细胞和气管表面上皮细胞以及甲状腺、气管和支气管中表达。DUOX1产生过氧化氢,这对甲状腺过氧化物酶和乳过氧化物酶至关重要。它还参与甲状腺激素合成和黏膜中乳过氧化物酶介导的抗菌防御。DUOX1在粘蛋白表达中也发挥作用,在胎儿组织中普遍表达。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

DUOX1 抗体 (H-9) 参考文献:

  1. 作为甲状腺 H(2)O(2) 生成系统组成部分的 ThOX 蛋白的特征。  |  De Deken, X., et al. 2002. Exp Cell Res. 273: 187-96. PMID: 11822874
  2. 双氧化酶是支持粘膜表面宿主防御的新型过氧化氢来源。  |  Geiszt, M., et al. 2003. FASEB J. 17: 1502-4. PMID: 12824283
  3. 鉴定 duox 的新伙伴:EFP1,一种硫代毒素相关蛋白。  |  Wang, D., et al. 2005. J Biol Chem. 280: 3096-103. PMID: 15561711
  4. 受精时的氧化爆发取决于双重氧化酶 Udx1 的激活。  |  Wong, JL., et al. 2004. Dev Cell. 7: 801-14. PMID: 15572124
  5. 培养的人气道上皮细胞中双氧化酶 1 依赖性 MUC5AC 粘蛋白的表达。  |  Shao, MX. and Nadel, JA. 2005. Proc Natl Acad Sci U S A. 102: 767-72. PMID: 15640347
  6. 人气道上皮细胞中的 Duox 可调节过氧化氢的产生。  |  Forteza, R., et al. 2005. Am J Respir Cell Mol Biol. 32: 462-9. PMID: 15677770
  7. 双氧化酶-2 具有依赖 Ca2+ 的内在 H2O2 生成活性。  |  Ameziane-El-Hassani, R., et al. 2005. J Biol Chem. 280: 30046-54. PMID: 15972824
  8. 甲状腺组织基因表达的等全基因变异。  |  He, H., et al. 2005. Thyroid. 15: 660-7. PMID: 16053381
  9. 呼吸道上皮细胞中 Th1 和 Th2 细胞因子对双重 NADPH 氧化酶/过氧化物酶 Duox1 和 Duox2 的不同调节作用  |  Harper, RW., et al. 2005. FEBS Lett. 579: 4911-7. PMID: 16111680
  10. 人类胎儿肺上皮细胞中DUOX1表达和功能的发育调节。  |  Fischer, H., et al. 2007. Am J Physiol Lung Cell Mol Physiol. 292: L1506-14. PMID: 17337509
  11. NADPH氧化酶DUOX1维持TGF-β1信号并促进肺纤维化。  |  Louzada, RA., et al. 2021. Eur Respir J. 57: PMID: 32764116
  12. ZC3H13通过m6A依赖性修饰减少喉鳞状细胞癌细胞中DUOX1介导的铁死亡。  |  Huang, L., et al. 2023. Tissue Cell. 84: 102187. PMID: 37536262

订购信息

产品名称产品编号规格价格数量收藏夹

DUOX1 抗体 (H-9)

sc-393096
200 µg/ml
$316.00

DUOX1 (H-9): m-IgG Fc BP-HRP 套装

sc-530353
200 µg Ab; 10 µg BP
$354.00

DUOX1 (H-9): m-IgGκ BP-HRP 套装

sc-523803
200 µg Ab, 40 µg BP
$354.00

DUOX1 (H-9): m-IgG1 BP-HRP 套装

sc-544007
200 µg Ab; 20 µg BP
$354.00

DUOX1 抗体 (H-9) AC

sc-393096 AC
500 µg/ml, 25% agarose
$416.00

DUOX1 抗体 (H-9) HRP

sc-393096 HRP
200 µg/ml
$316.00

DUOX1 抗体 (H-9) FITC

sc-393096 FITC
200 µg/ml
$330.00

DUOX1 抗体 (H-9) PE

sc-393096 PE
200 µg/ml
$343.00

DUOX1 抗体 (H-9) Alexa Fluor® 488

sc-393096 AF488
200 µg/ml
$357.00

DUOX1 抗体 (H-9) Alexa Fluor® 546

sc-393096 AF546
200 µg/ml
$357.00

DUOX1 抗体 (H-9) Alexa Fluor® 594

sc-393096 AF594
200 µg/ml
$357.00

DUOX1 抗体 (H-9) Alexa Fluor® 647

sc-393096 AF647
200 µg/ml
$357.00

DUOX1 抗体 (H-9) Alexa Fluor® 680

sc-393096 AF680
200 µg/ml
$357.00

DUOX1 抗体 (H-9) Alexa Fluor® 790

sc-393096 AF790
200 µg/ml
$357.00

Hi, I would like to know if this antibody(Anti-DUOX1 Antibody (H-9): sc-393096) works for rats. Could you please provide me some information.

Asked by: Huizhong
Thank you for your question. Based on our tests with this product, Anti-DUOX1 Antibody (H-9) is only recommended for detection of DUOX1 of human and mink origin by WB, IP, IF and ELISA. We do not have any internal data to support viability with samples from rat.
Answered by: Tech Support Europe
Date published: 2022-09-19

Are there any issues with using sc-393096: DUOX1 (H-9) mouse monoclonal primary antibody on mouse samples?

Asked by: Trav11
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-393096 conjugates.
Answered by: Technical Support
Date published: 2017-03-07
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Rated 1 out of 5 by from Did not workWe used this antibody in the ratio 1:500 but could not see any signal in 40ug of Beas2B cell lysate
Date published: 2017-08-07
Rated 5 out of 5 by from Great Ab for WBThis antibody is well-cited for a variety of applications including WB, IP, IF, and ELISA. Strong, clear signal with little to no background. Works well in a variety of species including mouse, rat, and human samples.
Date published: 2017-01-25
Rated 5 out of 5 by from Produced positive Western blot data of DUOX1Produced positive Western blot data of DUOX1 expression in H69AR, HCT-116, A549 and Mv 1 Lu whole cell lysates. -SCBT QC
Date published: 2014-04-17
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DUOX1 抗体 (H-9) is rated 3.7 out of 5 by 3.
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