DTG (CAS 97-39-2)

外观 :

Powder

物理状态 :

Solid

溶解度 :

Soluble in ethanol (25 mM), chloroform, DMSO (25 mM), and acetone. Insoluble inwater.

保存 :

Store at room temperature

熔点 :

176-178° C (lit.)

沸点 :

396.09° C at 760 mmHg (Predicted) (tautomer)

密度 :

1.1 g/cm³ at 20° C

折射率 :

n²⁰_D 1.59 (Predicted)

IC50 :

Sigma Receptor: IC₅₀ = 15 nM (human); Sigma 2 receptor: IC₅₀ = 52 nM (rat); Female germline-specific tumor suppressor gld-1: IC₅₀ = 5.21 µM (Caenorhabditis elegans); Protein Rev: IC₅₀ = 8.31 µM (Human immunodeficiency virus type 1 group M subtype B ); Glutamate NMDA receptor: IC₅₀ = 9.12 µM (rat)

Ki 数据 :

Sigma Receptor: K_i= 3.1 nM (human); Sigma 2 receptor: K_i= 12.8 nM (rat); Sigma-1 receptor: K_i= 41 nM (guinea pig)

pK值 :

pK_b: 10.32 (Predicted)

德国水公害等级 :

3

RTECS :

MF1400000

PubChem CID :

MDL 号码 :

MFCD00008513

EC号码 :

202-577-6

SMILES :

CC1=CC=CC=C1NC(=NC2=CC=CC=C2C)N