Dimebolin dihydrochloride (CAS 97657-92-6)

物理状态 :

Solid

溶解度 :

Soluble in ethanol (~3 mg/ml), DMSO (~10 mg/ml), DMF (~1 mg/ml), PBS, pH 7.2 (~10 mg/ml), and water (>25 mg/ml).

保存 :

Store at -20° C

折射率 :

n²⁰_D 1.63

IC50 :

Histamine H1 receptor: IC₅₀ = 0.16 µM (human); 5-HT6 receptor: IC₅₀ = 0.89 µM (human); Butyrylcholinesterase: IC₅₀ = 7.9 µM (human); Acetylcholinesterase: IC₅₀ = 45 µM (human); L-type calcium channel: IC₅₀ = 57 µM

Ki 数据 :

5-HT7 receptor: K_i= 8 nM (human); 5-HT6 receptor: K_i= 26 nM (human); 5-HT2c receptor: K_i= 76 nM (human); 5-HT1a receptor: K_i>100 nM (human)

RTECS :

UV0625000

PubChem CID :

Merck 索引 :

14: 10391

MDL 号码 :

MFCD01617545

SMILES :

CC1=CC2=C(C=C1)N(C3=C2CN(CC3)C)CCC4=CN=C(C=C4)C.Cl.Cl