Deferiprone CAS: 30652-11-0
MF: C7H9NO2
MW: 139.15
A chelator that removes transferrin and ferritin in vitro.

Deferiprone (CAS 30652-11-0)

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同义词: 3-hydroxy-1,2-dimethylpyridin-4-one
应用; A chelator that removes transferrin and ferritin in vitro
CAS号码: 30652-11-0
分子量: 139.15
分子式: C7H9NO2
* 参考分析证明 大量特定数据 (包括水 含量).
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Deferiprone, also described as 1,2-dimethyl-3-hydroxypyrid-4-one, is a hydroxypyrid-4-one compound utilized as a specific chelator of iron in biological systems. Deferiprone has been described in studies investigating the excretion of iron in iron overloaded systems, and the excreted chelated species in a study of iron overloaded rabbits demonstrates a specificity of Deferiprone for iron over copper, zinc, calcium and magnesium.


参考文献

1. Kontoghiorghes, G.J. 1985. Lancet. 1: 817. PMID: 2858689
2. Kontoghiorghes, G.J. 1986. Biochim. Biophys. Acta. 869: 141-146. PMID: 3942757
3. Kontoghiorghes, G.J. and Hoffbrand, A.V. 1986. Br. J. Haematol. 62: 607-613. PMID: 3964556
4. Kontoghiorghes, G.J., et al. 1987. Arzneimittelforschung. 37: 1099-1102. PMID: 3435580

外观 :
Needles
物理状态 :
Solid
溶解度 :
Soluble in Methanol and Water (hot)
保存 :
Store at -20° C
熔点 :
260° C (dec.)
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
2972
SMILES :
CC1=C(C(=O)C=CN1C)O

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引用1 - 11

PMID: # 24875174  Park, YG. et al. 2014. Neuroscience. 274: 187-97.

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