D-myo-Inositol-1,4,5-triphosphate, sodium salt CAS: 141611-10-1
MF: C6H12O15P3•3Na
MW: 486.0
A second messenger produced in cells by phospholipase C.

D-myo-Inositol-1,4,5-triphosphate, sodium salt (CAS 141611-10-1)

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备用名: Ins(1,4,5)P3; 1,4,5-IP3
应用; D-myo-Inositol-1,4,5-triphosphate, sodium salt is a second messenger produced in cells by phospholipase C
CAS号码: 141611-10-1
纯度: ≥98%
分子量: 486.0
分子式: C6H12O15P33Na
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).

D-myo-Inositol-1,4,5-triphosphate, sodium salt is a second messenger produced in cells by phospholipase C mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate. Binds to one of several Ins(1,4,5)P3 receptors, containing calcium channel domains. Binding of Ins(1,4,5)P3 to the receptor results in opening of the calcium channels and an increase in intracellular calcium.


参考文献

1. Streb, H., et al. 1983. Nature. 306: 67-69. PMID: 6605482
2. Yoshida, Y. and Imai, S. 1997. Jpn. J. Pharmacol. 74: 125-137. PMID: 9243320
3. Exton, J.H. 1996. Annu. Rev. Pharmacol. Toxicol. 36: 481-509. PMID: 8725399

外观 :
Lyophilized powder
物理状态 :
Solid
保存 :
Store at -20° C
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
16760520
SMILES :
[[email protected]]1([[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]]([[email protected]@H]1OP(=O)(O)[O-])O)OP(=O)(O)[O-])OP(=O)(O)[O-])O)O.[Na+].[Na+].[Na+]

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