Date published: 2025-9-6

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CXCR-3 抗体 (G-8): sc-137140

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说明书
  • CXCR-3 抗体 G-8 是小鼠单克隆 IgG1 κ,CXCR-3抗体, 在8篇文献中引用,规格为200 µg/ml
  • 免疫human物种的CXCR-3的氨基酸1-95
  • CXCR-3 抗体 (G-8) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 CXCR-3
  • 抗CXCR-3抗体(G-8)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取CXCR-3 (G-8): sc-137140免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是CXCR-3 Antibody (G-8) for WB applications. 的首选辅助检测试剂,这些试剂现与CXCR-3 Antibody (G-8) 打包提供(请参阅下面的订购信息)。

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関連項目

CXCR-3抗体(G-8)是一种IgG1κ小鼠单克隆CXCR-3抗体(也称为CD183抗体、CXCR3抗体或IP-10受体抗体),可通过WB、IP、IF和ELISA检测小鼠、大鼠和人源的CXCR-3蛋白。CXCR-3抗体(G-8)既可作为非偶联抗CXCR-3抗体形式,也可作为多种偶联形式的抗CXCR-3抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。C-X-C或α趋化因子家族的特征是一对半胱氨酸残基被一个氨基酸隔开,主要作为中性粒细胞的趋化剂。C-X-C家族包括IL-8、NAP-2、MSGA和基质细胞衍生因子-1(SDF-1)。SDF-1最初被描述为前B细胞刺激因子,但后来被证明对T细胞和单核细胞而非中性粒细胞具有强大的趋化作用。C-X-C家族的受体是G蛋白偶联的、七次跨膜结构域蛋白,包括IL-8RA、IL-8RB、CXCR-3和fusin(也称为LESTR或CXCR-4)。CXCR-3,也称为IP-10/MIG受体,介导C-X-C趋化因子IP-10和MIG的Ca2+动员和趋化。CXCR-3在IL-2激活的T淋巴细胞中高表达,但在静息T淋巴细胞、B淋巴细胞、单核细胞或粒细胞中不表达。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CXCR-3 抗体 (G-8) 参考文献:

  1. CXCR3、CXCL10 和 1 型糖尿病。  |  Antonelli, A., et al. 2014. Cytokine Growth Factor Rev. 25: 57-65. PMID: 24529741
  2. CXCR3 在神经系统疾病中的作用  |  Zhou, YQ., et al. 2019. Curr Neuropharmacol. 17: 142-150. PMID: 29119926
  3. CXCR3 在炎症和结直肠癌中的不同作用。  |  Abron, JD., et al. 2018. Oncotarget. 9: 17928-17936. PMID: 29707158
  4. CXCR3及其趋化因子配体在皮肤病和癌症中的作用  |  Kuo, PT., et al. 2018. Front Med (Lausanne). 5: 271. PMID: 30320116
  5. CXCR3变体及其配体在肿瘤微环境中的不同作用  |  Reynders, N., et al. 2019. Cells. 8: PMID: 31216755
  6. CXCR3 介导的信号在实体恶性肿瘤转移级联中的作用。  |  Cannon, A., et al. 2021. Biochim Biophys Acta Rev Cancer. 1876: 188628. PMID: 34560199
  7. 胶质母细胞瘤中 CXCR3 的双重性:揭示新型治疗方法的自分泌和旁分泌机制。  |  Chan, TYH., et al. 2023. Cell Death Dis. 14: 835. PMID: 38104126
  8. 在炎症刺激过程中,LAMP1 控制着 CXCL10-CXCR3 轴介导的巨噬细胞极化炎症调节。  |  Ye, Y., et al. 2024. Int Immunopharmacol. 132: 111929. PMID: 38555817
  9. 感染和自身免疫中表达 CXCR3 的 T 细胞  |  Rubinstein, A., et al. 2024. Front Biosci (Landmark Ed). 29: 301. PMID: 39206903
  10. 包裹 CXCR3 拮抗剂的磷脂酰丝氨酸外泌体模拟物可缓解骨质疏松症。  |  Kang, M., et al. 2024. Adv Funct Mater. 34: PMID: 39539387

订购信息

产品名称产品编号规格价格数量收藏夹

CXCR-3 抗体 (G-8)

sc-137140
200 µg/ml
$316.00

CXCR-3 (G-8): m-IgG Fc BP-HRP 套装

sc-527122
200 µg Ab; 10 µg BP
$354.00

CXCR-3 (G-8): m-IgG1 BP-HRP 套装

sc-532495
200 µg Ab; 20 µg BP
$354.00

CXCR-3 抗体 (G-8) AC

sc-137140 AC
500 µg/ml, 25% agarose
$416.00

CXCR-3 抗体 (G-8) HRP

sc-137140 HRP
200 µg/ml
$316.00

CXCR-3 抗体 (G-8) FITC

sc-137140 FITC
200 µg/ml
$330.00

CXCR-3 抗体 (G-8) PE

sc-137140 PE
200 µg/ml
$343.00

CXCR-3 抗体 (G-8) Alexa Fluor® 488

sc-137140 AF488
200 µg/ml
$357.00

CXCR-3 抗体 (G-8) Alexa Fluor® 546

sc-137140 AF546
200 µg/ml
$357.00

CXCR-3 抗体 (G-8) Alexa Fluor® 594

sc-137140 AF594
200 µg/ml
$357.00

CXCR-3 抗体 (G-8) Alexa Fluor® 647

sc-137140 AF647
200 µg/ml
$357.00

CXCR-3 抗体 (G-8) Alexa Fluor® 680

sc-137140 AF680
200 µg/ml
$357.00

CXCR-3 抗体 (G-8) Alexa Fluor® 790

sc-137140 AF790
200 µg/ml
$357.00

Hi, I'd be interested in a sample of your CXCR-3 Antibody (G-8): sc-137140 Could this be arranged? Thanks, Gaia

Asked by: GaiaCantelli
Thank you for your question. For a limited time we are offering a free 10 µg sample of our mouse monoclonal antibody, CXCR-3 (G-8): sc-137140. Please contact our Technical Service Department to request a free sample for testing. Please call us toll-free at (800) 457-3801 option 2, e-mail <scbt@scbt.com>, or use the live chat on our website.
Answered by: Technical Support
Date published: 2017-08-29

I need to use an antibody to detect the protein in samples of avian origin. Do you know if sc-137140: CXCR-3 (G-8) mouse monoclonal antibody will work?

Asked by: TinTin
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
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Rated 3 out of 5 by from No specific bandsI tested this antibody for western blotting on whole lysate of human keratinocytes and Anaplastic thyroid carcinoma cell line BHT-101 (30 µg). I used 1:500 dilution in 2.5% milk dissolved in TBS-0.1%Tween incubated over-night at 4°C. The antibody does not detect any specific band at the expected MW.
Date published: 2024-08-05
Rated 3 out of 5 by from Buon funzionamentoAbbiamo usufruito del campione prova di 10ul. Lo abbiamo testato su lisato cellulare di cellule Caco-2 (20ug di proteine totali). Risulatato soddisfacente. Il segnale è un po' debole ma abbastanza pulito e specifico
Date published: 2021-06-17
Rated 3 out of 5 by from OK antibody with several non-specific bandsI recently used this antibody to detect CXCR3 expressed in HEK 293T (a non-expressing cell line by PCR) that were transfected with N-ter flag tagged CXCR3 expression construct. The reactivity of this antibody overlapped with that of the anti-flag antibody for the most part however, this antibody did produce six relatively strong non-specific bands in the empty vector transfected cells as well as in U87MG cells another cell line that is negative by PCR and RNAseq. Best, AC
Date published: 2018-12-14
Rated 5 out of 5 by from Nice Western Blot data of CXCRNice Western Blot data of CXCR-3 expression in non-transfected and human CXCR-3 transfected 293T whole cell lysates. -SCBT QC
Date published: 2014-04-25
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CXCR-3 抗体 (G-8) is rated 3.5 out of 5 by 4.
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