Citric Acid Trisodium Salt CAS: 68-04-2
MF: C6H5O7•3Na
MW: 258.07
Used in the preparation of sodium citrate buffer for antigen unmasking in IHC.

Citric Acid Trisodium Salt (CAS 68-04-2)

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同义词: Trisodium citrate; Sodium citrate
应用; Used in the preparation of sodium citrate buffer for antigen unmasking in IHC
CAS号码: 68-04-2
纯度: ≥99%
分子量: 258.07
分子式: C6H5O73Na
* 参考分析证明 大量特定数据 (包括水 含量).
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As a conjugate base of a weak acid, Citric Acid Trisodium Salt can perform as a biological buffering agent because it resists changes in pH. Citric acid is one of a series of compounds responsible for the physiological oxidation of fats, carbohydrates and proteins to carbon dioxide and water. Often used to prepare sodium citrate buffer for antigen retrieval of tissue samples. The citrate solution is designed to break protein cross-links; thus, unmasking antigens and epitopes in formalin-fixed and paraffin embedded tissue sections, resulting in enhancing staining intensity of antibodies. Citrate has anticoagulant activity; as a calcium chelator, it forms complexes that disrupt the tendency of blood to clot.
Additional forms available:
Citric Acid Monohydrate (sc-203327)
Citric Acid, Anhydrous (sc-211113)
Sodium Citrate, Dihydrate (sc-203383)
Sodium citrate monobasic (sc-215869)
Sodium citrate tribasic hydrate (sc-236898)
Citrate Concentrated Solution (sc-294091)


参考文献

1. Vandemark, P.J., et al. 1964. J. Bacteriol. 88: 1602-1607. PMID: 14240945
2. Shi, S.R., et al. 1993. J. Histochem. Cytochem. 41: 1599-1604. PMID: 7691930
3. Echezarreta, G., et al. 1997. Sangre. 42: 369-375. PMID: 9424736
4. Uszyński, W., et al. 2007. Folia Histochem. Cytobiol. 45: 33-36. PMID: 17378243

用法 :
• For antigen retrieval, prepare a solution of 10 mM sodium citrate buffer, pH 6.0.
外观 :
Powder
物理状态 :
Solid
溶解度 :
Clear Colorless at 50mg/ml in Water
保存 :
Store at 4° C
熔点 :
≥150° C
仅供科研使用。不可用于诊断或治疗。
德国水公害等级 :
1
PubChem CID :
6224
MDL 号码 :
MFCD00012462
EC号码 :
200-675-3
SMILES :
C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.[Na+].[Na+].[Na+]

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