cis-ACCP (CAS 777075-44-2)

用法 :

cis-ACCP is supplied as a crystalline solid. A stock solution may be made by dissolving the cis-ACCP in an organic solvent purged with an inert gas. cis-ACCP is soluble in ethanol to a concentration of approximately 0.15 mg/ml.

Further dilutions of the stock solution into aqueous buffers or isotonic saline should be made prior to performing biological experiments. Ensure that the residual amount of organic solvent is insignificant, since organic solvents may have physiological effects at low concentrations. Organic solvent-free aqueous solutions of cis-ACCP can be prepared by directly dissolving the crystalline compound in aqueous buffers. The solubility of cis-ACCP in PBS, pH 7.2, is approximately 0.3 mg/ml. We do not recommend storing the aqueous solution for more than one day.

物理状态 :

Solid

溶解度 :

Soluble in ethanol (~0.15 mg/ml), and PBS pH7.2 (~0.3 mg/ml).

保存 :

Store at -20° C

密度 :

1.42 g/cm³ (Predicted)

折射率 :

n²⁰_D 1.54 (Predicted)

IC50 :

MMP-2: IC₅₀ = 4 µM (human); MMP-9: IC₅₀ = 20 µM (human)

pK值 :

pK_a: 0.85 (Predicted), pK_b: 9.71 (Predicted)

PubChem CID :

MDL 号码 :

MFCD11976901

SMILES :

C1CC[C@H]([C@H](C1)N)NC(=O)P(=O)(O)O