Date published: 2025-9-7

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ceruloplasmin 抗体 (H-3): sc-365205

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说明书
  • ceruloplasmin抗体(H-3)是小鼠单克隆IgG2b κ, 在2篇文献中引用,规格为200 µg/ml
  • 免疫human物种的ceruloplasmin的氨基酸121-180
  • 抗-ceruloplasmin 抗体 (H-3) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 ceruloplasmin
  • 抗ceruloplasmin抗体(H-3)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取ceruloplasmin (H-3): sc-365205免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2b BP-HRP">m-IgG2b BP-HRP是ceruloplasmin Antibody (H-3) 适用于 WB 应用。 的首选辅助检测试剂,这些试剂现与ceruloplasmin Antibody (H-3) 打包提供(请参阅下面的订购信息)。

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関連項目

ceruloplasmin抗体(H-3)是一种IgG2b κ小鼠单克隆铜蓝蛋白抗体,可通过WB、IP、IF和ELISA方法检测小鼠、大鼠和人类的铜蓝蛋白。ceruloplasmin抗体(H-3)既可以以非偶联的抗铜蓝蛋白抗体形式存在,也可以以多种偶联形式的抗铜蓝蛋白抗体存在,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。铜蓝蛋白(CP)是一种蓝色的血浆糖蛋白,在肝细胞中合成,并在全身运输铜。铜蓝蛋白也被称为铁氧化酶,是基因内三倍体的产物,由三个同源结构域组成。两种剪接变体CP-1和CP-2在特定组织中的表达有所不同。铜蓝蛋白mRNA在人类肝脏、巨噬细胞和淋巴细胞中表达。铜蓝蛋白结合铜,每个分子有六个或七个铜离子。它参与将Fe(II)转铁蛋白过氧化为Fe(III)转铁蛋白。铜蓝蛋白被蛋白水解降解为短形式,仍具有铁氧化酶活性。然而,只有完整的长形式才能催化铁加载到铁蛋白中,这表明铜蓝蛋白的结构完整性对于该酶有效催化铁加载到铁蛋白中是必不可少的。铜蓝蛋白还在体外诱导低密度脂蛋白氧化,这一作用取决于单个可螯合的铜原子的存在。铜蓝蛋白的一种糖基磷脂酰肌醇(GPI)锚定形式由Sertoli细胞表达,这可能是Sertoli细胞中的主要形式。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

ceruloplasmin 抗体 (H-3) 参考文献:

  1. 重新思考脑磷脂在脑铁代谢中的作用  |  Qian, ZM. and Ke, Y. 2001. Brain Res Brain Res Rev. 35: 287-94. PMID: 11423158
  2. 神经退行性疾病中的钙磷蛋白免疫反应。  |  Loeffler, DA., et al. 2001. Free Radic Res. 35: 111-8. PMID: 11697191
  3. 铜和脑磷脂蛋白与银屑病的相关性。  |  Rashmi, R., et al. 2010. Clin Chim Acta. 411: 1390-2. PMID: 20580696
  4. 铁的吸收和从脑磷脂到转铁蛋白的转移。  |  Eid, C., et al. 2014. Biochim Biophys Acta. 1840: 1771-81. PMID: 24418516
  5. 患有围产期心肌病的尼日利亚人的血清硒和脑磷脂。  |  Karaye, KM., et al. 2015. Int J Mol Sci. 16: 7644-54. PMID: 25853263
  6. Ceruloplasmin 可降低孕期呼吸爆发反应。  |  Varfolomeeva, EY., et al. 2016. Free Radic Res. 50: 909-19. PMID: 27266720
  7. 胎粪中ceruloplasmin、乳铁蛋白和髓过氧化物酶之间的相关性。  |  Skarżyńska, E., et al. 2017. J Trace Elem Med Biol. 43: 58-62. PMID: 27903408
  8. 肝蛋白和脑磷脂促进小鼠肾脏的铁代谢  |  Jiang, B., et al. 2016. Sci Rep. 6: 39470. PMID: 27991585
  9. 用于植入式生物电源的基于脑磷脂的自耐受生物阴极。  |  Aleksejeva, O., et al. 2021. Bioelectrochemistry. 140: 107794. PMID: 33744681
  10. 黄斑变性和血清脑磷脂升高。  |  Newsome, DA., et al. 1986. Invest Ophthalmol Vis Sci. 27: 1675-80. PMID: 3793397
  11. 脑磷脂在炎症中的保护作用。  |  Denko, CW. 1979. Agents Actions. 9: 333-6. PMID: 517330
  12. 脑磷脂在铁代谢中的作用  |  Roeser, HP., et al. 1970. J Clin Invest. 49: 2408-17. PMID: 5480864

订购信息

产品名称产品编号规格价格数量收藏夹

ceruloplasmin 抗体 (H-3)

sc-365205
200 µg/ml
$316.00

ceruloplasmin (H-3): m-IgG Fc BP-HRP 套装

sc-525866
200 µg Ab; 10 µg BP
$354.00

ceruloplasmin (H-3): m-IgG2b BP-HRP 套装

sc-549641
200 µg Ab; 10 µg BP
$354.00

ceruloplasmin 抗体 (H-3) AC

sc-365205 AC
500 µg/ml, 25% agarose
$416.00

ceruloplasmin 抗体 (H-3) HRP

sc-365205 HRP
200 µg/ml
$316.00

ceruloplasmin 抗体 (H-3) FITC

sc-365205 FITC
200 µg/ml
$330.00

ceruloplasmin 抗体 (H-3) PE

sc-365205 PE
200 µg/ml
$343.00

ceruloplasmin 抗体 (H-3) Alexa Fluor® 488

sc-365205 AF488
200 µg/ml
$357.00

ceruloplasmin 抗体 (H-3) Alexa Fluor® 546

sc-365205 AF546
200 µg/ml
$357.00

ceruloplasmin 抗体 (H-3) Alexa Fluor® 594

sc-365205 AF594
200 µg/ml
$357.00

ceruloplasmin 抗体 (H-3) Alexa Fluor® 647

sc-365205 AF647
200 µg/ml
$357.00

ceruloplasmin 抗体 (H-3) Alexa Fluor® 680

sc-365205 AF680
200 µg/ml
$357.00

ceruloplasmin 抗体 (H-3) Alexa Fluor® 790

sc-365205 AF790
200 µg/ml
$357.00

Through one paper, I found the ceruloplasmin antibody is your company. So I want to get some free sample to try whether it can be used for my experiment. Thank you.

Asked by: Aaron chen
Thank you for your question. Please contact Technical Service for information on how to obtain a sample.
Answered by: Technical Support
Date published: 2018-12-14

What is the recommended fixation method for immunofluorescence staining with ceruloplasmin (H-3): sc-365205 monoclonal antibody?

Asked by: AbPolly
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-02-27
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Rated 3 out of 5 by from DisappointI got Anti-ceruloplasmin Antibody (H-3)-sample from scbt. It worked great, so I purchased a full Anti-ceruloplasmin Antibody (H-3) antibody. However, the full one is not as good as the sample. The blot looks very dirty.
Date published: 2022-09-12
Rated 1 out of 5 by from Not working in WB conditioned medium C2C12Western blotting Dilution 1:1000 conditioned medium C2C12 Not signal
Date published: 2018-10-05
Rated 4 out of 5 by from I get the right protein band.i used the purified Cp, i get the signal at right size with SC antibody.
Date published: 2018-02-23
Rated 5 out of 5 by from Exceptional immunofluorescence cell surfaceExceptional immunofluorescence cell surface staining in formalin-fixed HepG2 cells. -SCBT QC
Date published: 2015-02-21
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ceruloplasmin 抗体 (H-3) is rated 3.6 out of 5 by 5.
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