Date published: 2025-9-8

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CD33 抗体 (P67.6): sc-19660

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说明书
  • CD33抗体(P67.6)是小鼠单克隆IgG1 κ, 在6篇文献中引用,规格为200 µg/ml
  • 针对human来源的CD33转染FMY9S5细胞
  • CD33 抗体 (P67.6) 推荐用于IF 和 FCM,检测human 来源的 CD33
  • CD33 抗体 (P67.6) 可偶联 琼脂糖 用于 IP; 还可偶联 藻红蛋白 或者 FITC 用于 IF, IHC(P) 和 FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取CD33 (P67.6): sc-19660免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是CD33 Antibody (P67.6). 的首选辅助检测试剂,这些试剂现与CD33 Antibody (P67.6) 打包提供(请参阅下面的订购信息)。

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関連項目

CD33抗体(P67.6)是一种IgG1 κ小鼠单克隆CD33抗体,可通过IF和FCM检测人源的CD33。CD33抗体(P67.6)既可以是非偶联的,也可以是多种偶联形式的抗CD33抗体。CD33是一种I型跨膜糖蛋白,可在骨髓中的粒细胞和巨噬细胞前体中发现,但在多能干细胞中不存在。CD33也可在外周血中的单核细胞中表达。它被用作一种标记,用于区分粒系白血病细胞与淋巴细胞或红系白血病细胞。CD33可能具有唾液酸依赖的细胞粘附分子的功能。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CD33 抗体 (P67.6) 参考文献:

  1. p75/AIRM-1 或 CD33 在急性髓性白血病中的表面表达和功能:CD33 的参与可诱导白血病细胞凋亡。  |  Vitale, C., et al. 2001. Proc Natl Acad Sci U S A. 98: 5764-9. PMID: 11320212
  2. 人类集落形成细胞的前体可通过 CD33 和 CD34 抗原的表达以及光散射特性与集落形成细胞区分开来。  |  Andrews, RG., et al. 1989. J Exp Med. 169: 1721-31. PMID: 2469766
  3. 造血干细胞中CD33的基因灭活,以实现急性髓细胞白血病的CAR T细胞免疫治疗。  |  Kim, MY., et al. 2018. Cell. 173: 1439-1453.e19. PMID: 29856956
  4. TREM2在调节阿尔茨海默病中的小胶质细胞病理学中起CD33下游作用。  |  Griciuc, A., et al. 2019. Neuron. 103: 820-835.e7. PMID: 31301936
  5. 人类髓系分化抗原 'gp67'(CD-33)单克隆抗体的特征。  |  Favaloro, EJ., et al. 1987. Dis Markers. 5: 215-25. PMID: 3502990
  6. 用于治疗急性髓细胞白血病的CD33靶向CAR-NK细胞。  |  Albinger, N., et al. 2022. Blood Cancer J. 12: 61. PMID: 35418180
  7. 一种能与正常和白血病人类髓系祖细胞反应的单克隆抗体。  |  Griffin, JD., et al. 1984. Leuk Res. 8: 521-34. PMID: 6590930
  8. 人类脐带血自然杀伤细胞亚群的早期骨髓造血抗原(CD33)表达。  |  Handgretinger, R., et al. 1993. Immunol Lett. 37: 223-8. PMID: 7505004
  9. 进一步研究纯化的骨髓和外周血 CD34+造血祖细胞中 HLA-DR, CD33 和 CD13 表面抗原的表达。  |  Pierelli, L., et al. 1993. Br J Haematol. 84: 24-30. PMID: 7687858
  10. CD33 作为细胞相互作用分子 sialoadhesin 家族新成员的特征。  |  Freeman, SD., et al. 1995. Blood. 85: 2005-12. PMID: 7718872
  11. 单个N-连接糖基化位点与I型凝集素CD22和CD33的配体识别调节有关。  |  Sgroi, D., et al. 1996. J Biol Chem. 271: 18803-9. PMID: 8702538
  12. Sialoadhesins--免疫球蛋白超家族中依赖于唾液酸的细胞识别分子家族。  |  Kelm, S., et al. 1996. Glycoconj J. 13: 913-26. PMID: 8981082

订购信息

产品名称产品编号规格价格数量收藏夹

CD33 抗体 (P67.6)

sc-19660
200 µg/ml
$316.00

CD33 (P67.6): m-IgG Fc BP-HRP 套装

sc-526588
200 µg Ab; 10 µg BP
$354.00

CD33 (P67.6): m-IgG1 BP-HRP 套装

sc-531961
200 µg Ab; 20 µg BP
$354.00

CD33 抗体 (P67.6) AC

sc-19660 AC
500 µg/ml, 25% agarose
$416.00

CD33 抗体 (P67.6) FITC

sc-19660 FITC
200 µg/ml
$330.00

CD33 抗体 (P67.6) PE

sc-19660 PE
200 µg/ml
$343.00

CD33 抗体 (P67.6) Alexa Fluor® 488

sc-19660 AF488
200 µg/ml
$357.00

CD33 抗体 (P67.6) Alexa Fluor® 546

sc-19660 AF546
200 µg/ml
$357.00

CD33 抗体 (P67.6) Alexa Fluor® 594

sc-19660 AF594
200 µg/ml
$357.00

CD33 抗体 (P67.6) Alexa Fluor® 647

sc-19660 AF647
200 µg/ml
$357.00

CD33 抗体 (P67.6) Alexa Fluor® 680

sc-19660 AF680
200 µg/ml
$357.00

CD33 抗体 (P67.6) Alexa Fluor® 790

sc-19660 AF790
200 µg/ml
$357.00

is it suitable for western blot?

Asked by: Vins
Thank you very much for your question. The sc-19660 is recommended for detection of CD33 of human origin by IF and FCM. If you have an interest in testing a free 10 µg sample of CD33 Antibody (P67.6) sc-19660 in western blot please contact Technical Service by phone or email or by Live Chat.
Answered by: SCBT Heidelberg Support
Date published: 2018-11-27

What negative control should be used when using the conjugated version of CD33 (P67.6): sc-19660 monoclonal antibody in flow cytometry?

Asked by: jenniferc
Thank you for your inquiry. We recommend using the isotype specific normal mouse IgG conjugated to the same fluorophore. For example, if you are using sc-19660 PE, then you would want to use normal mouse IgG1 PE, sc-2866.
Answered by: Technical Support 10
Date published: 2017-01-10
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Rated 5 out of 5 by from Great FCM and IF dataStrong FCM and IF results; need to see IHC and western data
Date published: 2017-01-13
Rated 5 out of 5 by from Provides excellent FCM and IF dataThe CD33 Antibody (P67.6) proves to work great for flow cytometry applications, as well as, immunofluorescence applications showing strong staining localized to the membrane.
Date published: 2016-12-23
Rated 5 out of 5 by from Produced excellent immunofluorescence membraneProduced excellent immunofluorescence membrane staining in methanol-fixed THP-1 cells. -SCBT QC
Date published: 2015-02-11
Rated 5 out of 5 by from Great FCM data of THPGreat FCM data of THP-1 cells. -SCBT QC
Date published: 2014-10-07
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CD33 抗体 (P67.6) is rated 5.0 out of 5 by 4.
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