Date published: 2025-9-7

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caveolin-3 抗体 (A-3): sc-5310

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说明书
  • caveolin-3 抗体 A-3 是小鼠单克隆 IgG1 κ,caveolin-3抗体, 在65篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于mouse物种的caveolin-3的N-terminus的氨基酸3-40之间
  • caveolin-3 抗体 (A-3) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 caveolin-3
  • 抗caveolin-3抗体(A-3)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取caveolin-3 (A-3): sc-5310免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 caveolin-3 抗体 (A-3) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与caveolin-3 抗体 (A-3) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

caveolin-3 抗体(A-3)是一种小鼠单克隆 IgG1 kappa 轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、免疫组织化学和酶联免疫吸附测定(ELISA)检测小鼠、大鼠和人类来源的 caveolin-3 蛋白。 酶联免疫吸附试验(ELISA)。caveolin-3单克隆抗体(A-3)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®结合物。Caveolin-3在形成囊泡的过程中起着至关重要的作用,囊泡是细胞膜上特殊的瓶状凹陷,对于细胞内吞作用和信号转导等多种细胞过程至关重要。这些结构在肌肉细胞中尤为重要,因为肌肉细胞中主要表达caveolin-3,它们有助于信号分子的分隔和脂质代谢的调节。caveolin-3的存在对于维持小泡的完整性和确保正常的细胞通讯至关重要,尤其是在应对机械应力和肌肉收缩时。此外,caveolin-3与其他caveolin和信号蛋白相互作用,有助于细胞信号通路的动态调节。了解Caveolin-3的功能和重要性有助于深入了解各种生理过程和潜在的病理状况,因此Caveolin-3单克隆抗体(A-3)成为研究肌肉生物学和相关领域的研究人员的重要工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

caveolin-3 抗体 (A-3) 参考文献:

  1. 洞穴素(Caveolin)是洞穴膜衣的蛋白质成分。  |  Rothberg, KG., et al. 1992. Cell. 68: 673-82. PMID: 1739974
  2. Caveolin-3和Caveolae调节心室复极化。  |  Markandeya, YS., et al. 2023. J Mol Cell Cardiol. 177: 38-49. PMID: 36842733
  3. Caveolin-3的硝化修饰:糖尿病前期动物心脏胰岛素抵抗的新机制和治疗缺血性心力衰竭的潜在靶点。  |  Meng, Z., et al. 2023. Circulation. 147: 1162-1179. PMID: 36883479
  4. Caveolin-3硝化作用导致糖尿病前期心脏胰岛素抵抗。  |  Sadoshima, J. 2023. Circulation. 147: 1180-1182. PMID: 37036910
  5. Caveolin-3和Caveolin-1相互作用可减少因Caveolin-3突变引起的通道功能障碍。  |  Benzoni, P., et al. 2024. Int J Mol Sci. 25: PMID: 38256054
  6. 3T3-L1 成纤维细胞分化为脂肪细胞时质膜的形态变化。  |  Fan, JY., et al. 1983. J Cell Sci. 61: 219-30. PMID: 6885939
  7. 从富含内皮细胞的来源中分离出的富含洞穴素的膜域的特征:对人类疾病的影响。  |  Lisanti, MP., et al. 1994. J Cell Biol. 126: 111-26. PMID: 7517942
  8. 上皮细胞中的VIP21/caveolin, 糖磷脂簇和糖基磷脂酰肌醇锚定蛋白的分拣。  |  Zurzolo, C., et al. 1994. EMBO J. 13: 42-53. PMID: 8306971
  9. 洞穴素-2 的鉴定, 序列和表达定义了洞穴素基因家族。  |  Scherer, PE., et al. 1996. Proc Natl Acad Sci U S A. 93: 131-5. PMID: 8552590
  10. 主要在肌肉中表达的洞穴素基因家族新成员洞穴素-3的分子克隆。  |  Tang, Z., et al. 1996. J Biol Chem. 271: 2255-61. PMID: 8567687
  11. src酪氨酸激酶对洞穴素的磷酸化。洞穴素的α-异构体在体内被v-Src选择性磷酸化。  |  Li, S., et al. 1996. J Biol Chem. 271: 3863-8. PMID: 8632005
  12. Caveolin-3在骨骼肌, 心肌和平滑肌细胞中的表达。Caveolin-3 是肌浆膜的组成部分,与肌营养不良蛋白和肌营养不良蛋白相关糖蛋白共同分化。  |  Song, KS., et al. 1996. J Biol Chem. 271: 15160-5. PMID: 8663016

订购信息

产品名称产品编号规格价格数量收藏夹

caveolin-3 抗体 (A-3)

sc-5310
200 µg/ml
$316.00

caveolin-3 (A-3): m-IgG Fc BP-HRP 套装

sc-526483
200 µg Ab; 10 µg BP
$354.00

caveolin-3 (A-3): m-IgG1 BP-HRP 套装

sc-531856
200 µg Ab; 20 µg BP
$354.00

caveolin-3 抗体 (A-3) AC

sc-5310 AC
500 µg/ml, 25% agarose
$416.00

caveolin-3 抗体 (A-3) HRP

sc-5310 HRP
200 µg/ml
$316.00

caveolin-3 抗体 (A-3) FITC

sc-5310 FITC
200 µg/ml
$330.00

caveolin-3 抗体 (A-3) PE

sc-5310 PE
200 µg/ml
$343.00

caveolin-3 抗体 (A-3) Alexa Fluor® 488

sc-5310 AF488
200 µg/ml
$357.00

caveolin-3 抗体 (A-3) Alexa Fluor® 546

sc-5310 AF546
200 µg/ml
$357.00

caveolin-3 抗体 (A-3) Alexa Fluor® 594

sc-5310 AF594
200 µg/ml
$357.00

caveolin-3 抗体 (A-3) Alexa Fluor® 647

sc-5310 AF647
200 µg/ml
$357.00

caveolin-3 抗体 (A-3) Alexa Fluor® 680

sc-5310 AF680
200 µg/ml
$357.00

caveolin-3 抗体 (A-3) Alexa Fluor® 790

sc-5310 AF790
200 µg/ml
$357.00

caveolin-3 (A-3) 中和勝肽

sc-5310 P
100 µg/0.5 ml
$68.00

Product: caveolin (A-3) sc-5310 What sensitivity has this product?

Asked by: Thodur
Thanks for your question. In order to determine antibody sensitivity please contact technical service.
Answered by: SCBT Heidelberg Support
Date published: 2019-01-06

My preferred goat anti-mouse secondary is no longer available. What secondary detection reagent do you recommend instead?

Asked by: Cweed
We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: TechService7
Date published: 2016-12-28
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Rated 5 out of 5 by from Excellent for immunofluorescent stainingWe initially requested a free sample of this antibody to test and ended up buying a full vial. Tested for immunofluorescent staining on FFPE section of skeletal muscle after citrate-based antigen retrieval, at a dilution of 1:100 in PBS with 0.01% Triton-X 100 and 5% normal serum. Incubated at 37 degrees C for 1 h. (secondary Ab: anti-mouse DyLite 594 @ 1:1000 for 1 h @ RT)
Date published: 2020-11-25
Rated 5 out of 5 by from Works well in cardiac cells and tissue (WB, IHC)- good results in WB from cardiac tissue and cells (concentration 1:500) - good results in IHC in PFA-fixed cardiac tissue and cells (concentration 1:200)
Date published: 2017-10-30
Rated 5 out of 5 by from specific stainingThis antibody gave a positive staining when use it detect caveolin-3 in mouse lung tissue, I obtained specific staining.
Date published: 2017-06-03
Rated 4 out of 5 by from Good antibodyNice bands in WB using 1/1000 antibody dilution. Fast ECL detection because of HRP coupling. To recommend.
Date published: 2017-03-21
Rated 5 out of 5 by from Great antibody for multiple purposesMonoclonal antibody validated for IHC with paraffin embedded sections and Western blot. Cited in multiple publications for chIP and IP.
Date published: 2016-12-20
Rated 3 out of 5 by from Nice antibodyThis antibody works nicley for WB although the signal is not so strong.
Date published: 2016-11-08
Rated 5 out of 5 by from It worked well for WBIt worked well for WB.
Date published: 2015-09-09
Rated 5 out of 5 by from Used in WB and IP in mouse cells and worked greatUsed in WB and IP in mouse cells and worked great.
Date published: 2015-08-04
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caveolin-3 抗体 (A-3) is rated 4.2 out of 5 by 13.
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