Btk Antibody (10d11): sc-81170
- Btk Antibody (10d11) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 1-175 of Btk of human origin
- recommended for detection of Btk of mouse, rat and human origin by WB and IP
- See Btk (E-9): sc-28387 for Btk antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Btk Antibody (10d11) for WB applications. These reagents are now offered in bundles with Btk Antibody (10d11) (see ordering information below).
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SEE ALSO...
Btk Antibody (10d11) is a mouse monoclonal IgG1 antibody that detects Bruton′s tyrosine kinase (Btk) in mouse, rat, and human samples through western blotting (WB) and immunoprecipitation (IP) applications. Btk plays a crucial role in B cell development and signaling, making Btk essential for the immune response. Mutations in the Btk gene can lead to X-linked agammaglobulinemia, a condition characterized by a significant reduction in B cells and immunoglobulins, which leaves individuals susceptible to infections. Btk is primarily located in the cytoplasm and is activated upon B cell receptor engagement, leading to downstream signaling that promotes cell survival and proliferation. Understanding the function and regulation of Btk is vital for developing targeted therapies for immunodeficiencies and certain types of cancers, as Btk dysregulation can contribute to malignancies. Anti-Btk antibody (10d11) is an invaluable tool for researchers studying B cell biology and related pathologies, providing reliable detection and analysis of this important protein.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Btk Antibody (10d11) | sc-81170 | 200 µg/ml | $322.00 | |||
Btk Antibody (10d11): m-IgG Fc BP-HRP Bundle | sc-539597 | 200 µg Ab; 10 µg BP | $361.00 | |||
Btk Antibody (10d11): m-IgG1 BP-HRP Bundle | sc-541585 | 200 µg Ab; 20 µg BP | $361.00 |