Date published: 2025-9-9

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Amphiphysin I 抗体 (A-7): sc-376435

5.0(3)
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说明书
  • Amphiphysin I抗体(A-7)是小鼠单克隆IgG1 (kappa轻链),规格为200 µg/ml
  • 特异性抗原位于human物种的Amphiphysin I的C-terminus的氨基酸667-695之间
  • 推荐用于 mouse, rat 和 human 来源的Amphiphysin I WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是Amphiphysin I Antibody (A-7) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Amphiphysin I Antibody (A-7) 打包提供(请参阅下面的订购信息)。

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    関連項目

    Amphiphysin是一种富含于大脑中的蛋白质,表现出N-末端脂质相互作用并作为二聚体发挥作用。Amphiphysin包含一个膜弯曲BAR结构域、一个中间Clathrin和适配器结合结构域以及一个C-末端SH3结构域。在大脑中,Amphiphysin I和II形成异二聚体,通过它们的SH3结构域与Clathrin相关的GTPase Dynamin结合。这种关联对于神经元中突触囊泡的循环至关重要,因为它先于Dynamin与Clathrin涂层坑的结合和随后的囊泡出芽。在其他组织中,Amphiphysin可能在其他膜弯曲和曲率稳定事件中发挥关键作用。哺乳动物Amphiphysins,即Amphiphysin I和Amphiphysin II,具有相似的总体结构。Amphiphysin II的一种普遍存在的剪接形式不包含Clathrin或适配器相互作用,在肌肉组织中高度表达,并参与T小管网络的形成和稳定。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Amphiphysin I 抗体 (A-7)

    sc-376435
    200 µg/ml
    $316.00

    Amphiphysin I (A-7): m-IgG Fc BP-HRP 套装

    sc-537986
    200 µg Ab; 10 µg BP
    $354.00

    Amphiphysin I (A-7): m-IgGκ BP-HRP 套装

    sc-535489
    200 µg Ab; 40 µg BP
    $354.00

    Amphiphysin I (A-7): m-IgG1 BP-HRP 套装

    sc-545477
    200 µg Ab; 20 µg BP
    $354.00

    Amphiphysin I (A-7) 中和勝肽

    sc-376435 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-376435 P appropriate for?

    Asked by: Cweed
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-27
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    Rated 5 out of 5 by from Nice results in western blot using mouse brainNice results in western blot using mouse brain, rat brain and human hippocampus tissue extracts. -SCBT QC
    Date published: 2015-07-20
    Rated 5 out of 5 by from Works well for western blot with transfectedWorks well for western blot with transfected lysates. -SCBT QC
    Date published: 2015-05-01
    Rated 5 out of 5 by from Produced superb immunofluorescence cytoplasmicProduced superb immunofluorescence cytoplasmic staining in methanol-fixed HeLa cells. -SCBT QC
    Date published: 2015-03-26
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    Amphiphysin I 抗体 (A-7) is rated 5.0 out of 5 by 3.
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