alpha-Linolenic Acid CAS: 463-40-1
MF: C18H30O2
MW: 278.43
A polyunsaturated essential fatty acid.

α-Linolenic Acid (CAS 463-40-1)

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备用名: Octadeca-9Z,12Z,15Z-trienoic acid; α-Lnn; cis,cis,cis-9,12,15-Octadecatrienoic acid
应用; α-Linolenic Acid is a polyunsaturated essential fatty acid
CAS号码: 463-40-1
纯度: >98%
分子量: 278.43
分子式: C18H30O2
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).

α-Linolenic Acid (ALA), an 18 carbon polyunsaturated essential fatty acid, has been found to exert in vitro anti-inflammatory effects in murine intestine. Mechanistic studies suggest that this compound decreases TNFα (tumor necrosis factor-α) secretion levels as well as NF-κB activation. Additionally, ALA has been noted to be a reactive oxygen species scavenger that temporarily improves cell proliferation. Further experiments report that an increase in ALA levels seems to be correlated inversely with plasma IL-6 (interleukin-6) soluble receptor levels.


参考文献

1. Dai, J., et al. 2010. Am. J. Clin. Nutr. 92: 177-185. PMID: 20463041
2. Couëdelo, L., et al. 2010. Br. J. Nutr. 1-10. PMID: 21080982
3. Geleijnse, J.M., et al. 2010. Curr Atheroscler Rep. 12: 359-367. PMID: 20814766
4. Hassan, A., et al. 2010. J. Nutr. 140: 1714-1721. PMID: 20724486
5. Hennessy, A.A., et al. 2010. Lipids. [Epub ahead of print]. PMID: 21161605
6. Steinritz, D., et al. 2010. Toxicol. Sci. 118: 521-529. PMID: 20833707

物理状态 :
Liquid
保存 :
Store at -20° C
熔点 :
-11° C (lit.)
沸点 :
230-232° C at 1 mmHg
密度 :
0.92 g/ml
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
MDL 号码 :
MFCD00065720
EC号码 :
207-334-8
SMILES :
CC/C=C\\C/C=C\\C/C=C\\CCCCCCCC(=O)O

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PMID: # 28973946  Lopez, MS. et al. 2017. Proc. Natl. Acad. Sci. U.S.A. 114: 11223-11228.

PMID: # 26681780  J Lipid Res. 207-18.

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