Date published: 2025-10-10

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Alix 抗体 (2H12): sc-53539

4.4(5)
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说明书
  • Alix抗体(2H12)是小鼠单克隆IgG1 κ, 在11篇文献中引用,规格为200 µg/ml
  • 推荐用于 mouse, rat, human 和 Xenopus 来源的Alix WB, IP, IF 和 ELISA检测
  • 看 Alix (1A12): sc-53540,可查看有标记的 Alix 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是Alix Antibody (2H12) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Alix Antibody (2H12) 打包提供(请参阅下面的订购信息)。

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関連項目

ALG-2相互作用蛋白(Alix),也称为程序性细胞死亡6相互作用蛋白(PDCD6相互作用蛋白),是一种细胞质蛋白。 Alix与凋亡相关蛋白(ALG-2和PDCD6)和内吞作用调节因子CIN85相互作用。此外,Alix与运输所需的内体分选复合物(ESCRT)蛋白(Tsg101和CHMP4)相互作用,并且可以与HIV-1结合。内吞素(SH3P4、SH3P8和SH3P13)是改变膜曲率的酶,在包膜囊泡形成的早期和晚期步骤中是必需的,也与Alix结合。 Alix参与多囊体的货物蛋白的浓缩和分选,以将其整合到囊泡中。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Alix 抗体 (2H12)

sc-53539
200 µg/ml
$316.00

Alix (2H12): m-IgG Fc BP-HRP 套装

sc-536983
200 µg Ab; 10 µg BP
$354.00

Alix (2H12): m-IgGκ BP-HRP 套装

sc-534162
200 µg Ab; 40 µg BP
$354.00

Alix (2H12): m-IgG1 BP-HRP 套装

sc-544939
200 µg Ab; 20 µg BP
$354.00

Are there any issues with using sc-53539: Alix (2H12) mouse monoclonal primary antibody on mouse samples?

Asked by: Germaine
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-53539 conjugates.
Answered by: Technical Support
Date published: 2017-03-07

What is the lower mw band with the nuclear extract.   Is that an Alix isoform or contaminate ?

Asked by: Roger Madison
Thank you for your question. We have not further characterized the lower molecular weight band observed in the nuclear extracts tested (HeLa, Jurkat, K-562, THP-1 and U-937) by Western blot with this Alix Antibody (2H12): sc-53539. However, this band is also observed with a different Alix antibody with a different epitope, sc-53540: Alix (1A12).
Answered by: Technical Support
Date published: 2016-12-20
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Rated 5 out of 5 by from Good antibody for WBThe Alix Antibody (2H12): sc-53539 works well for Western blot applications. This antibody has also been cited several times for further verification.
Date published: 2017-01-18
Rated 4 out of 5 by from Worked with transfected lysate by WBWorked with transfected lysate by WB -SCBT QC
Date published: 2015-04-28
Rated 4 out of 5 by from Publishable data in WB using mouse brainPublishable data in WB using mouse brain tumor exosomes -SCBT Publication Review
Date published: 2015-03-14
Rated 5 out of 5 by from Bands seen in WB using HeLaBands seen in WB using HeLa, Jurkat, K-562, THP-1 and U-937 nuclear extracts. -SCBT QC
Date published: 2015-01-10
Rated 4 out of 5 by from Publishable data in IP using mouse C2C12(myoblastPublishable data in IP using mouse C2C12(myoblast cell line) -SCBT Publication Review
Date published: 2013-01-24
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Alix 抗体 (2H12) is rated 4.4 out of 5 by 5.
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