Aladin Antibody (G-12): sc-376133
- Aladin Antibody (G-12) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 501-531 near the C-terminus of Aladin of human origin
- recommended for detection of Aladin of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including bovine
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Aladin Antibody (G-12) for WB applications. These reagents are now offered in bundles with Aladin Antibody (G-12) (see ordering information below).
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SEE ALSO...
Aladin Antibody (G-12) is a mouse monoclonal IgG2b antibody that detects Aladin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Aladin is a member of the WD repeat-containing protein family, which is known for its diverse roles in cellular processes, including signal transduction regulation and RNA processing. Aladin is predominantly located in the cytoplasm and nucleus, where Aladin is crucial for the development of the peripheral and central nervous systems. This localization enables Aladin to participate in essential cellular functions, including gene expression regulation and cellular signaling pathways vital for neuronal health and function. Defects in Aladin are linked to the autosomal recessive disorder known as achalasia-addisonianism-alacrima (triple A) syndrome, which manifests through symptoms such as achalasia, alacrima, and adrenal insufficiency. Robust expression of Aladin in neural tissues correlates with the cognitive, motor, and sensory dysfunctions observed in patients with triple A syndrome, highlighting Aladin′s importance in maintaining neurological integrity. Anti-Aladin antibody (G-12) serves as an invaluable tool for researchers investigating Aladin′s role in various biological contexts and disease states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Aladin Antibody (G-12) | sc-376133 | 200 µg/ml | $322.00 | |||
Aladin Antibody (G-12): m-IgG Fc BP-HRP Bundle | sc-537969 | 200 µg Ab; 10 µg BP | $361.00 | |||
Aladin Antibody (G-12): m-IgGκ BP-HRP Bundle | sc-535465 | 200 µg Ab; 40 µg BP | $361.00 | |||
Aladin (G-12) Neutralizing Peptide | sc-376133 P | 100 µg/0.5 ml | $69.00 |