Date published: 2025-9-6

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AGR2 抗体 (6C5): sc-101211

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说明书
  • AGR2 抗体 6C5 是小鼠单克隆 IgG2b κ,AGR2抗体, 在9篇文献中引用,规格为100 µg/ml
  • 免疫human物种的重组AGR2
  • 推荐用于 mouse, rat 和 human 来源的AGR2 WB, IP 和 ELISA检测
  • 关于如何获取AGR2 (6C5): sc-101211免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 2b BP-HRP">m-IgG2b BP-HRP是AGR2 Antibody (6C5) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与AGR2 Antibody (6C5) 打包提供(请参阅下面的订购信息)。

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関連項目

AGR2抗体(6C5)是一种IgG2b κ小鼠单克隆AGR2抗体(也称为AGR2抗体),可通过WB、IP和ELISA检测到小鼠、大鼠和人类来源的AGR2蛋白。AGR2抗体(6C5)为非偶联形式的抗AGR2抗体。AGR2(前梯度蛋白2),也称为AG2、GOB-4或HAG-2,是前梯度同源家族的一员。它是XAG-2的人类同源物,XAG-2是分泌的非洲爪蟾前梯度蛋白。在非洲爪蟾中,它参与水泥腺分化和神经标记基因表达。AGR2是由两种不同的AGR2转录本编码的分泌蛋白。它与LYPD3和α-肌营养不良聚糖(DAG-1)相互作用。AGR2在前列腺癌、乳腺癌、肺癌、肾癌和子宫内膜癌中普遍表达且表达上调。AGR2的表达与雌激素受体(ER)的表达呈正相关,与表皮生长因子受体(EGFR)的表达呈负相关。AGR2可能作为各种癌症的潜在治疗标志物。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

AGR2 抗体 (6C5) 参考文献:

  1. 人类乳腺癌细胞系 T47D 和抗雌激素衍生物 T47D-r 的蛋白质组和基因组分析比较。  |  Huber, M., et al. 2004. Mol Cell Proteomics. 3: 43-55. PMID: 14557597
  2. AGR2,一种在前列腺癌中过度表达的雄激素诱导分泌蛋白。  |  Zhang, JS., et al. 2005. Genes Chromosomes Cancer. 43: 249-59. PMID: 15834940
  3. 与乳腺癌相关的新型转移诱导因子--水泥腺蛋白的人类同源物。  |  Liu, D., et al. 2005. Cancer Res. 65: 3796-805. PMID: 15867376
  4. 评估作为炎症性肠病候选基因的 AGR2 和 AGR3。  |  Zheng, W., et al. 2006. Genes Immun. 7: 11-8. PMID: 16222343
  5. 在法国检测到新的耐甲氧西林金黄色葡萄球菌克隆,其中含有导致医院和社区感染的中毒性休克综合征毒素 1 基因。  |  Durand, G., et al. 2006. J Clin Microbiol. 44: 847-53. PMID: 16517865
  6. 乳腺癌中 AGR2 表达的预后相关性。  |  Fritzsche, FR., et al. 2006. Clin Cancer Res. 12: 1728-34. PMID: 16551856
  7. 诱导转移蛋白 AGR2 对接受激素治疗的乳腺癌患者预后的影响。  |  Innes, HE., et al. 2006. Br J Cancer. 94: 1057-65. PMID: 16598187
  8. 前梯度-2表达量的增加与前列腺癌患者的生存率较低有很大关系。  |  Zhang, Y., et al. 2007. Prostate Cancer Prostatic Dis. 10: 293-300. PMID: 17457305
  9. 通过转移期和阵列比较基因组杂交对基因组畸变进行高分辨率分析,确定肺癌细胞系中的候选肿瘤基因。  |  Zhu, H., et al. 2007. Cancer Lett. 245: 303-14. PMID: 16517066

订购信息

产品名称产品编号规格价格数量收藏夹

AGR2 抗体 (6C5)

sc-101211
100 µg/ml
$333.00

AGR2 (6C5): m-IgG2b BP-HRP 套装

sc-548474
100 µg Ab; 10 µg BP
$354.00

Hi, which epitope does the antibody target? Or in which general region of the protein is this epitope situated?

Asked by: Evaeva
Thank you for your question. This antibody was raised against recombinant AGR2 of human origin. The exact binding epitope has not been mapped. If you have any further questions, please contact your local distributor or technical service.
Answered by: Tech Service
Date published: 2019-11-06

What is the recommended secondary reagent to be used with this mouse monoclonal primary?

Asked by: jerojero
We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 7
Date published: 2017-02-15
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Rated 5 out of 5 by from Very Good antibodyThis month I tested AGR2 Antibody (6C5) and I got very good results. Good antibody, no back grown, very clean blot
Date published: 2019-07-10
Rated 5 out of 5 by from Excellent antibody for WBprobed at 1/1000X dilution and the blot turned out perfect. Great antibody.
Date published: 2017-09-22
Rated 5 out of 5 by from this product works all right in IFthis antibody I bought three weeks ago, worked good in th IF assay.
Date published: 2017-02-07
Rated 5 out of 5 by from Good in Western BlotStrong detection of AGR2 seen with both whole cell lysates and transfected samples in Western Blot.
Date published: 2017-01-17
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AGR2 抗体 (6C5) is rated 4.8 out of 5 by 5.
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