Adrenic Acid (22:4, n-6) CAS: 28874-58-0
MF: C22H36O2
MW: 332.5
A polyunsaturated fatty acid believed to be a source of arachidonic acid.

Adrenic Acid (22:4, n-6) (CAS 28874-58-0)

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同义词: cis-7,10,13,16-Docosatetraenoic acid
应用; A polyunsaturated fatty acid believed to be a source of arachidonic acid
CAS号码: 28874-58-0
纯度: ≥96%
分子量: 332.5
分子式: C22H36O2
* 参考分析证明 大量特定数据 (包括水 含量).
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Adrenic Acid (22-4,n-6), also known as 7,10,13,16-Docosatetraenoic acid, is a polyunsaturated fatty acid. Peroximal β-oxidation of 7,10,13,16-docosatetraenoic acid has been shown to form arachidonic acid. Endothelial cells have been shown to convert arachidonic acid to docosatetraenoic acid and releasing docosatetraenoic acid when exposed to ionophore A23187 (sc-3591). Additionally, endothelial cell studies have demonstrated that adrenic acid reduces prostaglandin 12.


参考文献

1. Campbell, W.B., et al. 1985. Biochim. Biophys. Acta. 837: 67-76. PMID: 3931686
2. Mann, C.J., et al. 1986. Arch. Biochem. Biophys. 244: 813-823. PMID: 3080955
3. Baykousheva, S.P., et al. 1994. J. Biol. Chem. 269: 18390-18394. PMID: 8034586
4. Krämer, S.D., et al. 2002. In Vitro Cell. Dev. Biol. Anim. 38: 566-571. PMID: 12762838
5. McNamara, R.K., et al. 2010. Eur J Pharmacol. [Epub ahead of print]. PMID: 21118685

外观 :
Oil
物理状态 :
Liquid
溶解度 :
Soluble in ethanol, hexane, methylene chloride, DMSO (100 mg/ml), DMF (100 mg/ml), and PBS pH 7.4. Insoluble in water.
保存 :
Store at -20° C
沸点 :
439.49° C at 760 mmHg
密度 :
0.92 g/mL
折射率 :
n20D 1.50
仅供科研使用。不可用于诊断或治疗。
德国水公害等级 :
3
PubChem CID :
5497181
MDL 号码 :
MFCD00673435
SMILES :
CCCCCC=CCC=CCC=CCC=CCCCCCC(=O)O

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PMID: # 21118685  McNamara, RK. et al. 2011. Eur. J. Pharmacol. 652: 152-156.

引用1 - 11
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