5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (CAS 66611-26-5)

物理状态 :

Solid

保存 :

Store at room temperature

IC50 :

5-hydroxytryptamine 1B receptor: IC₅₀ = 2 nM (rat); 5-hydroxytryptamine 1A receptor: IC₅₀ = 14 nM (rat); 5-HT1d receptor: IC₅₀ = 39 nM (human); 5-HT6 receptor: IC₅₀ = 79 nM (human); 5-HT2c receptor: IC₅₀ = 290 nM (human)

Ki 数据 :

5-HT1a receptor: K_i= 2 nM (rat); 5-HT1b receptor: K_i= 2 nM (rat); 5-HT1d receptor: K_i= 2 nM (rat); 5-HT2c receptor: K_i= 400 nM (human); 5-HT2a receptor: K_i= 780 nM (rat)

pK值 :

pK_b: 9.51 (Predicted)

PubChem CID :

MDL 号码 :

MFCD09864704

SMILES :

COC1=CC2=C(C=C1)NC=C2C3=CCNCC3