5-Fluoroorotic acid monohydrate (CAS 220141-70-8)

外观 :

Crystalline

物理状态 :

Solid

溶解度 :

Soluble in water, DMSO, and :1 Ammonium Hydroxide:Water (50 mg/ml with Gentle Heating).

保存 :

Store at -20° C

熔点 :

254-256° C

折射率 :

n²⁰_D 1.58 (Predicted)

IC50 :

Janus kinase 2 mutant JAK2V617F: IC₅₀ = 4.12 µM; Mycobacterium Tuberculosis in 7H9 Media: IC₅₀ = 4.58 µM; JAK2: IC₅₀ = 5.96 µM (human)

Ki 数据 :

Trypanosoma cruzi dihydroorotate dehydrogenase: K_i= 19.3 µM

RTECS :

UV7800000

PubChem CID :

MDL 号码 :

MFCD00150658

SMILES :

C1(=C(NC(=O)NC1=O)C(=O)O)F.O