Molecular structure of 1-Phenylbiguanide hydrochloride, CAS Number: 55-57-2
1-Phenylbiguanide hydrochloride (CAS 55-57-2)
Application:
1-Phenylbiguanide hydrochloride is a SR-3 agonist
CAS Number:
55-57-2
Molecular Weight:
213.67
Molecular Formula:
C8H11N5•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
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SDS & Certificate of Analysis
1-Phenylbiguanide hydrochloride is a 5-HT3 receptor agonist.
1-Phenylbiguanide hydrochloride (CAS 55-57-2) References
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- Extreme Basicity of Biguanide Drugs in Aqueous Solutions: Ion Transfer Voltammetry and DFT Calculations. | Langmaier, J., et al. 2016. J Phys Chem A. 120: 7344-50. PMID: 27564915
- Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies. | Tonelli, M., et al. 2017. Eur J Med Chem. 127: 781-792. PMID: 27823885
- 5-HTR3 and 5-HTR4 located on the mitochondrial membrane and functionally regulated mitochondrial functions. | Wang, Q., et al. 2016. Sci Rep. 6: 37336. PMID: 27874067
- Breathing stimulation mediated by 5-HT1A and 5-HT3 receptors within the preBötzinger complex of the adult rabbit. | Iovino, L., et al. 2019. Brain Res. 1704: 26-39. PMID: 30244021
- Phenformin, But Not Metformin, Delays Development of T Cell Acute Lymphoblastic Leukemia/Lymphoma via Cell-Autonomous AMPK Activation. | Vara-Ciruelos, D., et al. 2019. Cell Rep. 27: 690-698.e4. PMID: 30995468
- The Surprising Effect of Phenformin on Cutaneous Darkening and Characterization of Its Underlying Mechanism by a Forward Chemical Genetics Approach. | Takano, K., et al. 2020. Int J Mol Sci. 21: PMID: 32093380
- Synthesis, Antitumor Evaluation, Molecular Modeling and Quantitative Structure-Activity Relationship (QSAR) of Novel 2-[(4-Amino-6-N-substituted-1,3,5-triazin-2-yl)methylthio]-4-chloro-5-methyl-N-(1H-benzo[d]imidazol-2(3H)-ylidene)Benzenesulfonamides. | Tomorowicz, Ł., et al. 2020. Int J Mol Sci. 21: PMID: 32331219
- Effect of sarpogrelate treatment on 5-HT modulation of vascular sympathetic innervation and platelet activity in diabetic rats. | Fernández-González, JF., et al. 2022. Biomed Pharmacother. 153: 113276. PMID: 35717784
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Activator of:
SR-3A.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1-Phenylbiguanide hydrochloride, 100 mg | sc-203455 | 100 mg | $59.00 |